中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
EVALUATION AND ANAL YSIS OF DRUG-USE IN HOSPITALS OF CHINA
2015年
5期
646-648
,共3页
抑酸制剂%围术期%用药治疗干预%临床药师
抑痠製劑%圍術期%用藥治療榦預%臨床藥師
억산제제%위술기%용약치료간예%림상약사
Acid-suppressive agents%Perioperative%Drug treatment interventions%Clinical pharmacist
目的：了解抑酸制剂在外科的使用情况，进一步规范抑酸制剂的临床应用，探索临床药师干预临床辅助用药的模式。方法：全面调查干预前（2009—2011年）及干预后（2012年）3类切口手术（污染手术、清洁-污染手术、清洁手术）出院病例资料，对围术期抑酸制剂的使用情况进行对照分析。结果：经临床药师干预后，围术期预防性应用抑酸制剂在适应证、药物选择、用法与用量等方面的合理性均明显提高（ P＜0.05）；患者住院时间、抑酸制剂使用时间、抑酸制剂费用和住院药品总费用占住院总费用的比例均有所降低。结论：临床药师分析不合理用药情况，找到临床干预靶点，通过干预单病种围术期抑酸制剂治疗方案，将干预模式推广至其他单病种的药物治疗，并为临床药师参与并制定单病种临床路径提供了可行、有效的工作模式。
目的：瞭解抑痠製劑在外科的使用情況，進一步規範抑痠製劑的臨床應用，探索臨床藥師榦預臨床輔助用藥的模式。方法：全麵調查榦預前（2009—2011年）及榦預後（2012年）3類切口手術（汙染手術、清潔-汙染手術、清潔手術）齣院病例資料，對圍術期抑痠製劑的使用情況進行對照分析。結果：經臨床藥師榦預後，圍術期預防性應用抑痠製劑在適應證、藥物選擇、用法與用量等方麵的閤理性均明顯提高（ P＜0.05）；患者住院時間、抑痠製劑使用時間、抑痠製劑費用和住院藥品總費用佔住院總費用的比例均有所降低。結論：臨床藥師分析不閤理用藥情況，找到臨床榦預靶點，通過榦預單病種圍術期抑痠製劑治療方案，將榦預模式推廣至其他單病種的藥物治療，併為臨床藥師參與併製定單病種臨床路徑提供瞭可行、有效的工作模式。
목적：료해억산제제재외과적사용정황，진일보규범억산제제적림상응용，탐색림상약사간예림상보조용약적모식。방법：전면조사간예전（2009—2011년）급간예후（2012년）3류절구수술（오염수술、청길-오염수술、청길수술）출원병례자료，대위술기억산제제적사용정황진행대조분석。결과：경림상약사간예후，위술기예방성응용억산제제재괄응증、약물선택、용법여용량등방면적합이성균명현제고（ P＜0.05）；환자주원시간、억산제제사용시간、억산제제비용화주원약품총비용점주원총비용적비례균유소강저。결론：림상약사분석불합리용약정황，조도림상간예파점，통과간예단병충위술기억산제제치료방안，장간예모식추엄지기타단병충적약물치료，병위림상약사삼여병제정단병충림상로경제공료가행、유효적공작모식。
OBJECTIVE:To investigate the perioperative use of the acid-suppressive agents in surgical patients so as to standardize the clinical application of acid-suppressive agents, and to explore the clinical pharmacists'intervention model on the use of adjuvant drugs. METHODS: The medical records of the discharged patients undergoing operations ( contaminated surgery, aseptic-contaminated surgery, aseptic surgery ) before and after the intervention ( 2009-2011 vs.2012 ) were reviewed for comparative analysis regarding the use of acid-suppressive agents.RESULTS: The perioperative prophylactic use of acid-suppressive agents were significantly more rational in indications, drug selection, and usage and dosage after clinical pharmacists'intervention than before intervention ( P<0.05), and the hospital stay, administration duration of antacids, proportion of drug costs in total hospitalization costs were all decreased after intervention.CONCLUSIONS:Clinical pharmacists find out the clinical intervention targets by analyzing the irrational use of drugs.The intervention model on perioperative acid-suppressive therapy can be applied to drug use for other diseases and it provides feasible and effective working model for clinical pharmacists to be involved in the formulation of clinical pathway of single disease.
