中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
EVALUATION AND ANAL YSIS OF DRUG-USE IN HOSPITALS OF CHINA
2015年
5期
622-624
,共3页
李忠文%林锦信%陈志江%麦韵屏
李忠文%林錦信%陳誌江%麥韻屏
리충문%림금신%진지강%맥운병
空腹血糖受损%腰围%新发糖尿病%发病风险%相关性
空腹血糖受損%腰圍%新髮糖尿病%髮病風險%相關性
공복혈당수손%요위%신발당뇨병%발병풍험%상관성
Impaired fasting glucose%Waist circumference%New onset of diabetes%Risk%Correlation
目的：研究空腹血糖受损人群腰围变化与新发糖尿病发病风险的相关性。方法：回顾性分析广东省人民医院2011年10月—2012年10月、2013年10月—2014年10月进行健康体检的人群资料，从中选取符合标准的空腹血糖受损人群640例作为研究对象，按照基线腰围测量值将其分为4组，比较各组人群的糖尿病发病率，并采用多因素Logistic回归分析对腰围变化和新发糖尿病发病风险的相关性进行分析。结果：空腹血糖受损人群的患病率随腰围增加而逐渐升高；男性发病率（14.63％，79／540）低于女性（15.00％，15／100）（P＜0.05）。多因素Logistic回归分析结果显示，校正性别、年龄等因素后，第二、三、四分位组较第一分位组的空腹血糖受损发病风险均增大；不同性别校正上述因素后，男性第二、三、四分位组较第一分位组空腹血糖受损发病风险显著增加（ P＜0.01）。结论：新发糖尿病的发病风险，将随着空腹血糖受损人群腰围的增加而不断加大，且腰围水平为第四分位组可作为空腹血糖受损防控的主要人群。
目的：研究空腹血糖受損人群腰圍變化與新髮糖尿病髮病風險的相關性。方法：迴顧性分析廣東省人民醫院2011年10月—2012年10月、2013年10月—2014年10月進行健康體檢的人群資料，從中選取符閤標準的空腹血糖受損人群640例作為研究對象，按照基線腰圍測量值將其分為4組，比較各組人群的糖尿病髮病率，併採用多因素Logistic迴歸分析對腰圍變化和新髮糖尿病髮病風險的相關性進行分析。結果：空腹血糖受損人群的患病率隨腰圍增加而逐漸升高；男性髮病率（14.63％，79／540）低于女性（15.00％，15／100）（P＜0.05）。多因素Logistic迴歸分析結果顯示，校正性彆、年齡等因素後，第二、三、四分位組較第一分位組的空腹血糖受損髮病風險均增大；不同性彆校正上述因素後，男性第二、三、四分位組較第一分位組空腹血糖受損髮病風險顯著增加（ P＜0.01）。結論：新髮糖尿病的髮病風險，將隨著空腹血糖受損人群腰圍的增加而不斷加大，且腰圍水平為第四分位組可作為空腹血糖受損防控的主要人群。
목적：연구공복혈당수손인군요위변화여신발당뇨병발병풍험적상관성。방법：회고성분석광동성인민의원2011년10월—2012년10월、2013년10월—2014년10월진행건강체검적인군자료，종중선취부합표준적공복혈당수손인군640례작위연구대상，안조기선요위측량치장기분위4조，비교각조인군적당뇨병발병솔，병채용다인소Logistic회귀분석대요위변화화신발당뇨병발병풍험적상관성진행분석。결과：공복혈당수손인군적환병솔수요위증가이축점승고；남성발병솔（14.63％，79／540）저우녀성（15.00％，15／100）（P＜0.05）。다인소Logistic회귀분석결과현시，교정성별、년령등인소후，제이、삼、사분위조교제일분위조적공복혈당수손발병풍험균증대；불동성별교정상술인소후，남성제이、삼、사분위조교제일분위조공복혈당수손발병풍험현저증가（ P＜0.01）。결론：신발당뇨병적발병풍험，장수착공복혈당수손인군요위적증가이불단가대，차요위수평위제사분위조가작위공복혈당수손방공적주요인군。
OBJECTIVE:To study the correlation between the waist circumference and the onset risk of diabetes in patients with impaired fasting glucose.METHODS:A retrospective analysis was performed on the data of the patients receiving health examination in Guangdong Provincial Hospital from Oct.2011 to Oct.2012 or from Oct.2013 to Oct. 2014, from which, 640 patients with impaired fasting blood glucose meeting our inclusion criteria were enrolled and assigned to four groups based on the baseline waist circumference.The incidence of diabetes was compared among the four groups, and the relationship between waist circumference and onset risk of diabetes was analyzed using multivariate logistic regression analysis.RESULTS:The incidence of diabetes in patients with impaired fasting glucose increased accompanied with the increase of their waist circumference;the incidence rate of diabetes was lower for men (14.63%, 79/540 ) than for women ( 15.00%, 15/100 ) ( P <0.05 ) .Multivariate Logistic regression analysis showed that after adjusting gender, age and other factors, the risk of impaired fasting glucose in the second, third and fourth quartile groups was higher than in the first quartile group ( P <0.01 ); after adjusting the above factors for patients of different gender, the risk of impaired fasting glucose was higher in the second and third quartile male groups than in the first quartile male group (P<0.01).CONCLUSIONS:The risk of new onset of diabetes increases with the increasing of waist circumference in patients with impaired fasting glucose, and the forth quartile group in terms of waist circumference level can be taken as the target population with regard to impaired fasting glucose control.
