局解手术学杂志
跼解手術學雜誌
국해수술학잡지
JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY
2015年
3期
277-278,279
,共3页
Wolffian管肿瘤%临床病理学特征%免疫组化%诊断及鉴别诊断
Wolffian管腫瘤%臨床病理學特徵%免疫組化%診斷及鑒彆診斷
Wolffian관종류%림상병이학특정%면역조화%진단급감별진단
Wolfffian adnexal tumor%clinicopathological features%immunohistochemistry%diagnosis and differential diagnosis
目的:探讨Wolffian管附件肿瘤( Wolfffian adnexal tumor,WAT)的临床病理学特征及免疫组化。方法对1例发生于阔韧带的WAT进行临床病理特征分析和免疫组织化学观察。结果肿瘤位于阔韧带,呈带蒂有包膜的囊实性肿块,组织学可见大小腺管紧密排列、筛状及实性区结构。免疫组织化学显示肿瘤细胞pan-cytokeratin、Vimentin、CK18、CD99阳性表达, alpha-in-hibin灶性阳性;calretinin、CD10、EMA、ER、PR、Syn、CA15-3和CA19-9阴性,Ki-67指数小于5%。 PAS染色腺样结构周围基底膜阳性。结论 WAT主要依靠病理组织学、免疫组化和具有特征性的wolffian管残件结构诊断。
目的:探討Wolffian管附件腫瘤( Wolfffian adnexal tumor,WAT)的臨床病理學特徵及免疫組化。方法對1例髮生于闊韌帶的WAT進行臨床病理特徵分析和免疫組織化學觀察。結果腫瘤位于闊韌帶,呈帶蒂有包膜的囊實性腫塊,組織學可見大小腺管緊密排列、篩狀及實性區結構。免疫組織化學顯示腫瘤細胞pan-cytokeratin、Vimentin、CK18、CD99暘性錶達, alpha-in-hibin竈性暘性;calretinin、CD10、EMA、ER、PR、Syn、CA15-3和CA19-9陰性,Ki-67指數小于5%。 PAS染色腺樣結構週圍基底膜暘性。結論 WAT主要依靠病理組織學、免疫組化和具有特徵性的wolffian管殘件結構診斷。
목적:탐토Wolffian관부건종류( Wolfffian adnexal tumor,WAT)적림상병이학특정급면역조화。방법대1례발생우활인대적WAT진행림상병리특정분석화면역조직화학관찰。결과종류위우활인대,정대체유포막적낭실성종괴,조직학가견대소선관긴밀배렬、사상급실성구결구。면역조직화학현시종류세포pan-cytokeratin、Vimentin、CK18、CD99양성표체, alpha-in-hibin조성양성;calretinin、CD10、EMA、ER、PR、Syn、CA15-3화CA19-9음성,Ki-67지수소우5%。 PAS염색선양결구주위기저막양성。결론 WAT주요의고병리조직학、면역조화화구유특정성적wolffian관잔건결구진단。
Objective To explore the clinicopathological and immunohistochemical features of wolffian adnexal tumour ( WAT) . Meth-ods The clinical and pathological features analysis and immunohistochemistry methods were utilized to study the histopathology features of a case Wolffian adnexal tumor. Results One case of unilateral WAT which located in broad ligament display a solid-cystic mass with pedicled and enveloped,its histology showed large and small tubulars,screen structure and solid zone. Its immunohistochemistry staining was positive for pan-cytokeratin,vimentin,CK18 and CD99,positive staining for α-inhibin in a little tumor cell,and negative for calretinin,CD10,EMA, ER,PR,Syn,CA15-3,CA19-9,Ki-67 index is less than 5%. PAS positive staining for the basement membrane around Gland like structure. Conclusion Wolffian adnexal tumour is diagnosised by its histopathological,immunohistochemical and it’ s distinctive location where Wolffi-an duct remnants are found.