局解手术学杂志
跼解手術學雜誌
국해수술학잡지
JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY
2015年
3期
273-276
,共4页
王瑜%马宽生%陈健%宋举贤
王瑜%馬寬生%陳健%宋舉賢
왕유%마관생%진건%송거현
射频消融术%肝动脉化疗栓塞术%早期肝癌%肝硬化
射頻消融術%肝動脈化療栓塞術%早期肝癌%肝硬化
사빈소융술%간동맥화료전새술%조기간암%간경화
radiofrequency ablation%transcatheter hepatic arterial chemoembolization%early hepatocellular carcinoma%liver cirrhosis
目的：评估射频消融术( RFA)联合肝动脉化疗栓塞术( TACE)与单独射频消融术治疗合并肝硬化的早期肝细胞癌(HCC)的疗效。方法回顾性分析2008年1月至2013年12月在我院行RFA(n=53)和RFA+TACE(n=51)患者的临床资料,对2组患者人口统计学资料、手术过程、术后并发症、术后恢复情况及随访情况进行比较。结果随访(37.6±12.3)个月,76例生存,38例死亡。 RFA+TACE组和RFA组的1年、3年、5年无瘤生存率分别为75.4%、47.3%、32.6%和63.1%、37.2%、22.4%。RFA+TACE组和RFA组的1年、3年、5年总生存率分别为96.5%、78.7%、65.9%和94.3%、75.6%、62.3%。结论对于合并肝硬化早期肝癌患者,RFA+TACE治疗比单独使用RFA治疗具有更高的无瘤生存率,而总体生存率无差异。
目的：評估射頻消融術( RFA)聯閤肝動脈化療栓塞術( TACE)與單獨射頻消融術治療閤併肝硬化的早期肝細胞癌(HCC)的療效。方法迴顧性分析2008年1月至2013年12月在我院行RFA(n=53)和RFA+TACE(n=51)患者的臨床資料,對2組患者人口統計學資料、手術過程、術後併髮癥、術後恢複情況及隨訪情況進行比較。結果隨訪(37.6±12.3)箇月,76例生存,38例死亡。 RFA+TACE組和RFA組的1年、3年、5年無瘤生存率分彆為75.4%、47.3%、32.6%和63.1%、37.2%、22.4%。RFA+TACE組和RFA組的1年、3年、5年總生存率分彆為96.5%、78.7%、65.9%和94.3%、75.6%、62.3%。結論對于閤併肝硬化早期肝癌患者,RFA+TACE治療比單獨使用RFA治療具有更高的無瘤生存率,而總體生存率無差異。
목적：평고사빈소융술( RFA)연합간동맥화료전새술( TACE)여단독사빈소융술치료합병간경화적조기간세포암(HCC)적료효。방법회고성분석2008년1월지2013년12월재아원행RFA(n=53)화RFA+TACE(n=51)환자적림상자료,대2조환자인구통계학자료、수술과정、술후병발증、술후회복정황급수방정황진행비교。결과수방(37.6±12.3)개월,76례생존,38례사망。 RFA+TACE조화RFA조적1년、3년、5년무류생존솔분별위75.4%、47.3%、32.6%화63.1%、37.2%、22.4%。RFA+TACE조화RFA조적1년、3년、5년총생존솔분별위96.5%、78.7%、65.9%화94.3%、75.6%、62.3%。결론대우합병간경화조기간암환자,RFA+TACE치료비단독사용RFA치료구유경고적무류생존솔,이총체생존솔무차이。
Objective To assess the effect of radiofrequency ablation ( RFA) combined with transcatheter hepatic arterial chemoemboli-zation ( TACE) and radiofrequency ablation alone for the treatment of early hepatocellular carcinoma ( HCC) with liver cirrhosis. Methods The data of all the patients that were given RFA+TACE (n=51) and RFA (n=53) treatments in our hospital from January 2008 to De-cember 2013 were analyzed. The demographic data,process of operation,postoperative complications,postoperative recovery and follow-up of the patients in two groups were carefully compared. Results The average follow-up time was (37. 6 ± 20. 7)months,38 cases were dead and 76 cases were survival. The overall survival rates of 1 years,3 years,5 years after operation were respectively 96. 5%,78. 7%,65. 9% in RFA+TACE group and 94. 3%,75. 6%,62. 3% in RFA group. Tumor-free survival rates of 1 years,3 years,5 years were 75. 4%,47. 3%, 32. 6% in RFA+TACE group,and 63. 1%,37. 2%,22. 4% in RFA group. Conclusion For patients with early hepatocellular carcinoma with liver cirrhosis,RFA combined with TACE have higher tumor free survival rate than RFA alone in the treatment of early hepatocellular carcinoma,but no difference in overall survival rate. The results still need to be validated by prospectively randomized controlled trials.
