CAJ | 학술논문

目的：探讨七氟醚麻醉维持中不同年龄段患者血压的改变及最适浓度。方法按常规手术安排顺序收入择期行腹腔镜胆囊切除术( LC)患者60例,常规诱导,全程吸入七氟醚维持麻醉,按年龄分为青年组34例,中年组20例,老年组6例。记录诱导前及麻醉维持后10 min(T1)、20 min(T2)、30 min(T3)、60 min(T4)的SBP、DBP、MAP、呼气末七氟醚浓度(CETsev)及各浓度下患者例数、年龄。结果麻醉维持后血压波动在正常范围,维持后MAP在诱导前MAP ±20%范围内波动。各时间点不同CETsev下患者年龄比较差异无统计学意义(P>0.05)。各时间点不同CETsev下患者年龄段构成比差异无统计学意义(P>0.05)。随麻醉时间延长,0%~1%CETsev下患者例数由35例下降至11例,1%~2%时由10例上升至20例,2%~3%时维持在14例左右。结论 CETsev对不同年龄段患者血压的影响近似,2%~3%CETsev在各年龄段是既能满足手术需要,又能维持循环稳定的最适浓度。
목적：탐토칠불미마취유지중불동년령단환자혈압적개변급최괄농도。방법안상규수술안배순서수입택기행복강경담낭절제술( LC)환자60례,상규유도,전정흡입칠불미유지마취,안년령분위청년조34례,중년조20례,노년조6례。기록유도전급마취유지후10 min(T1)、20 min(T2)、30 min(T3)、60 min(T4)적SBP、DBP、MAP、호기말칠불미농도(CETsev)급각농도하환자례수、년령。결과마취유지후혈압파동재정상범위,유지후MAP재유도전MAP ±20%범위내파동。각시간점불동CETsev하환자년령비교차이무통계학의의(P>0.05)。각시간점불동CETsev하환자년령단구성비차이무통계학의의(P>0.05)。수마취시간연장,0%~1%CETsev하환자례수유35례하강지11례,1%~2%시유10례상승지20례,2%~3%시유지재14례좌우。결론 CETsev대불동년령단환자혈압적영향근사,2%~3%CETsev재각년령단시기능만족수술수요,우능유지순배은정적최괄농도。
Objective To investigate the effect of sevoflurane on blood pressure in patients with different ages and the optimal concen-tration of sevoflurane. Methods 60 patients underwent selective LC operation with conventional induction and sevoflurane maintenance were divided into three groups:the youth group (34 patients), the middle age group (20 patients) and the older age group (6 patients). The SBP, DBP, MAP, CETsev, number of patients, age of patients before induction and 10 min(T1), 20 min(T2), 30 min (T3), 60 min (T4) after induction were recorded. Results Fluctuate of blood pressure were in the normal range after anesthesia maintenance, and MAP were fluctuated within the range of ± 20% before induction. The age under different CETsev were of no significant difference in each time point (P>0. 05). The age composition ratio in different CETsev were of no significant difference in each time point (P>0. 05). As the time of anesthesia extended, the number of patients under 0% ~1%CETsev decreased from 35 to 11; the number of patients under 1% ~2%CETsev increased from 10 to 20;and the number of patients under 2% ~3%CETsev maintened in 14 approximately. Conclusion The effect of sevoflurane on blood pressure of different ages is approximate. 2% ~3% CETsev is the most optimal concentration during the main-tenance of anesthesia.