中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2015年
5期
261-264
,共4页
王毓琴%黄玉宜%方海珍%戴玛莉%郑美琴%向圣锦%吕帆
王毓琴%黃玉宜%方海珍%戴瑪莉%鄭美琴%嚮聖錦%呂帆
왕육금%황옥의%방해진%대마리%정미금%향골금%려범
葡萄膜炎,前%超声生物显微镜%眼前半段
葡萄膜炎,前%超聲生物顯微鏡%眼前半段
포도막염,전%초성생물현미경%안전반단
Uveitis,anterior%Ultrasound biomicroscopy%Anterior eye segment
目的 观察急性前葡萄膜炎(AAU)治疗前后眼前节的UBM扫描图像特点,评价UBM在AAU治疗中的监测价值.方法 前瞻性观察性研究.温州医科大学附属眼视光医院45例(45眼)AAU患者纳入研究,炎症程度为中至重度.患者于治疗前以及当裂隙灯显微镜观察到患眼前房细胞和玻璃体细胞消失时行UBM检查,测量房角开放角度(AA500)、房角开放距离(AOD500)和睫状体厚度(CBT)等参数.采用配对t检验进行统计学分析.结果 患眼治疗前各个象限的AA500、AOD500、CBT均大于对侧健眼,差异有统计学意义(t=3.752、3.950、5.277、6.350、5.455,P＜0.01).经过治疗炎症消退后,患眼AA500、AOD500、CBT较治疗前减小(t=-16.990、3.964、5.373、6.360、5.629,P＜0.01),和对侧健眼比较差异无统计学意义(t=-0.189、-0.296、-0.371、-1.693、-0.811,P＞0.05).结论 AAU患者的AA500、AOD500和CBT在炎症的发展和消退过程中发生动态变化,UBM可实时监测AAU治疗前后眼前节结构的变化规律,为AAU的诊治提供客观依据.
目的 觀察急性前葡萄膜炎(AAU)治療前後眼前節的UBM掃描圖像特點,評價UBM在AAU治療中的鑑測價值.方法 前瞻性觀察性研究.溫州醫科大學附屬眼視光醫院45例(45眼)AAU患者納入研究,炎癥程度為中至重度.患者于治療前以及噹裂隙燈顯微鏡觀察到患眼前房細胞和玻璃體細胞消失時行UBM檢查,測量房角開放角度(AA500)、房角開放距離(AOD500)和睫狀體厚度(CBT)等參數.採用配對t檢驗進行統計學分析.結果 患眼治療前各箇象限的AA500、AOD500、CBT均大于對側健眼,差異有統計學意義(t=3.752、3.950、5.277、6.350、5.455,P＜0.01).經過治療炎癥消退後,患眼AA500、AOD500、CBT較治療前減小(t=-16.990、3.964、5.373、6.360、5.629,P＜0.01),和對側健眼比較差異無統計學意義(t=-0.189、-0.296、-0.371、-1.693、-0.811,P＞0.05).結論 AAU患者的AA500、AOD500和CBT在炎癥的髮展和消退過程中髮生動態變化,UBM可實時鑑測AAU治療前後眼前節結構的變化規律,為AAU的診治提供客觀依據.
목적 관찰급성전포도막염(AAU)치료전후안전절적UBM소묘도상특점,평개UBM재AAU치료중적감측개치.방법 전첨성관찰성연구.온주의과대학부속안시광의원45례(45안)AAU환자납입연구,염증정도위중지중도.환자우치료전이급당렬극등현미경관찰도환안전방세포화파리체세포소실시행UBM검사,측량방각개방각도(AA500)、방각개방거리(AOD500)화첩상체후도(CBT)등삼수.채용배대t검험진행통계학분석.결과 환안치료전각개상한적AA500、AOD500、CBT균대우대측건안,차이유통계학의의(t=3.752、3.950、5.277、6.350、5.455,P＜0.01).경과치료염증소퇴후,환안AA500、AOD500、CBT교치료전감소(t=-16.990、3.964、5.373、6.360、5.629,P＜0.01),화대측건안비교차이무통계학의의(t=-0.189、-0.296、-0.371、-1.693、-0.811,P＞0.05).결론 AAU환자적AA500、AOD500화CBT재염증적발전화소퇴과정중발생동태변화,UBM가실시감측AAU치료전후안전절결구적변화규률,위AAU적진치제공객관의거.
Objective To investigate dynamic changes in the ocular anterior segment in patients with acute anterior uveitis (AAU) using ultrasound biomicroscopy (UBM) and to assess the evaluation of UBM during the treatment of AAU.Methods In this prospective,observational study,45 eyes from 45 patients with moderate to severe AAU were examined.UBM was performed before (within 5 days of AAU attack) and after treatment of AAU (no anterior chamber cells or vitreous cells were observed by slit lamp microscopy).Angle opening angle (AA~),angle opening distance (AOD~0),and ciliary body thickness (CBT) were measured.The results were analyzed by paired t-test.Results Before treatment,the AA~0,AOD~0 and CBT values in each quadrant of the eyes with AAU were significantly higher than those in normal contralateral eyes (t=3.752,3.950,5.277,6.350,5.455,P＜0.01).With treatment,the inflammation was controlled gradually 4-6 weeks after AAU onset.AA~0,AOD~0 and CBT values of eyes with AAU were significantly reduced (t=-16.990,3.964,5.373,6.360,5.629,P＜0.01),and there were no significant differences compared to normal contralateral eyes (t=-0.189,-0.296,-0.371,-1.693,-0.811,P＞0.05).Conclusion UBM reveals dynamic morphologic changes in the ocular anterior segment structure before and after treatment in patients with AAU.This could provide important information in the development and treatment of AAU.
