中国卒中杂志
中國卒中雜誌
중국졸중잡지
CHINESE JOURNAL OF STROKE
2015年
7期
557-562
,共6页
颈动脉狭窄%颅内动脉狭窄%支架
頸動脈狹窄%顱內動脈狹窄%支架
경동맥협착%로내동맥협착%지가
Carotid stenosis%Intracranial artery stenosis%Stent
目的：比较单纯颈动脉支架置入术治疗和联合颈动脉、大脑中动脉支架置入术治疗症状性颈动脉狭窄伴有中动脉狭窄的缺血性卒中或短暂性脑缺血发作（transient ischemic attack，TIA）患者短期终点事件发生率。方法回顾2010年1月～2013年12月采用血管内支架治疗症状性颈动脉狭窄伴有同侧大脑中动脉狭窄的缺血性卒中或TIA患者的临床资料。根据治疗情况将患者分为单纯颈动脉支架置入术治疗组和联合颈动脉、大脑中动脉支架置入术治疗组。比较两组术后90 d终点事件（包括同侧缺血性卒中复发、症状性脑出血及死亡风险）的发生率。结果共有21例患者纳入本研究，男性15例，女性6例，平均年龄（58.5±3.6）岁，其中16例患者进行了颈动脉支架治疗，5例患者进行了颈动脉联合中动脉支架治疗。颈动脉支架治疗组90 d终点事件发生3例（18.75%），颈动脉联合中动脉支架治疗组发生1例终点事件（20%），两组间差异无显著性（P=0.952）。两组发生的终点事件均为缺血性卒中复发，无症状性脑出血及死亡患者。结论对于伴有颈动脉及大脑中动脉狭窄的缺血性卒中或TIA患者，与单纯颈动脉支架治疗相比同时进行颈动脉及大脑中动脉支架治疗手术未减少术后90 d同侧缺血性卒中复发风险。
目的：比較單純頸動脈支架置入術治療和聯閤頸動脈、大腦中動脈支架置入術治療癥狀性頸動脈狹窄伴有中動脈狹窄的缺血性卒中或短暫性腦缺血髮作（transient ischemic attack，TIA）患者短期終點事件髮生率。方法迴顧2010年1月～2013年12月採用血管內支架治療癥狀性頸動脈狹窄伴有同側大腦中動脈狹窄的缺血性卒中或TIA患者的臨床資料。根據治療情況將患者分為單純頸動脈支架置入術治療組和聯閤頸動脈、大腦中動脈支架置入術治療組。比較兩組術後90 d終點事件（包括同側缺血性卒中複髮、癥狀性腦齣血及死亡風險）的髮生率。結果共有21例患者納入本研究，男性15例，女性6例，平均年齡（58.5±3.6）歲，其中16例患者進行瞭頸動脈支架治療，5例患者進行瞭頸動脈聯閤中動脈支架治療。頸動脈支架治療組90 d終點事件髮生3例（18.75%），頸動脈聯閤中動脈支架治療組髮生1例終點事件（20%），兩組間差異無顯著性（P=0.952）。兩組髮生的終點事件均為缺血性卒中複髮，無癥狀性腦齣血及死亡患者。結論對于伴有頸動脈及大腦中動脈狹窄的缺血性卒中或TIA患者，與單純頸動脈支架治療相比同時進行頸動脈及大腦中動脈支架治療手術未減少術後90 d同側缺血性卒中複髮風險。
목적：비교단순경동맥지가치입술치료화연합경동맥、대뇌중동맥지가치입술치료증상성경동맥협착반유중동맥협착적결혈성졸중혹단잠성뇌결혈발작（transient ischemic attack，TIA）환자단기종점사건발생솔。방법회고2010년1월～2013년12월채용혈관내지가치료증상성경동맥협착반유동측대뇌중동맥협착적결혈성졸중혹TIA환자적림상자료。근거치료정황장환자분위단순경동맥지가치입술치료조화연합경동맥、대뇌중동맥지가치입술치료조。비교량조술후90 d종점사건（포괄동측결혈성졸중복발、증상성뇌출혈급사망풍험）적발생솔。결과공유21례환자납입본연구，남성15례，녀성6례，평균년령（58.5±3.6）세，기중16례환자진행료경동맥지가치료，5례환자진행료경동맥연합중동맥지가치료。경동맥지가치료조90 d종점사건발생3례（18.75%），경동맥연합중동맥지가치료조발생1례종점사건（20%），량조간차이무현저성（P=0.952）。량조발생적종점사건균위결혈성졸중복발，무증상성뇌출혈급사망환자。결론대우반유경동맥급대뇌중동맥협착적결혈성졸중혹TIA환자，여단순경동맥지가치료상비동시진행경동맥급대뇌중동맥지가치료수술미감소술후90 d동측결혈성졸중복발풍험。
Objective To compare short end events of simple carotid artery stent implantation (CAS) and carotid artery, middle cerebral artery stent implantation (CAS+PTAS) treatment for symptomatic carotid stenosis accompanied by artery stenosis in ischemic stroke or transient ischemic attack (TIA) in patients. Methods We were retrospectively studied the TIA or ischemic stroke patients who had carotid artery stenosis and ipsilateral middle arterial stenosis. All patients were treated with stent implantation. Patients were divided into CAS group and CAS+PTAS group. The outcomes were compared between groups and the primary outcomes were ischemic stroke, symptomatic intracranial hemorrhage and all cause of death during 90 days of follow-up. Results A total of 21 patients included in this study with an average age of (58.5±3.6) years old and 15 cases were male. There were 16 patients in the CAS group and 5 patients in the CAS+PTAS group. There were 3 (18.75%) end points in CAS group and 1 end point in the CAS+PTAS group. There was no statistical difference between the two groups (P=0.952). There was no intracranial hemorrhage and all cause of death in both groups. Conclusion Compared with the CAS treatment, CAS+PTAS treatment does not reduce the recurrent ischemic stroke risk in patients with carotid artery stenosis and ipsilateral middle arterial stenosis.
