CAJ | 학술논문

目的评价冷冻球囊消融(cryoballoon-based ablation,CBA)在阵发性心房颤动(房颤)治疗中的应用,分析其有效性、安全性及相关临床参数.方法选择2013年12月至2014年12月在上海交通大学医学院附属瑞金医院接受CBA的阵发性房颤患者107例,其中男72例,女35例,年龄19 ～ 80(59.63±10.11)岁.观察CBA的安全性、有效性、手术时间及随访数据.结果 106例(99.1％)的患者都应用冷冻球囊完成房颤消融手术(达到3根及以上肺静脉电隔离);术中4根肺静脉隔离率97.2％;手术及围术期,出现缺血性脑卒中、动静脉瘘各1例,膈神经受损2例.术后6个月随访时,86.0％的患者维持窦性心律.手术后急性期无房颤的患者在6个月时能维持窦性心律的比例显著增高(94.4％对64.3％,P=0.021).结论 CBA可有效安全地应用于阵发性房颤肺静脉隔离.
목적 평개냉동구낭소융(cryoballoon-based ablation,CBA)재진발성심방전동(방전)치료중적응용,분석기유효성、안전성급상관림상삼수.방법 선택2013년12월지2014년12월재상해교통대학의학원부속서금의원접수CBA적진발성방전환자107례,기중남72례,녀35례,년령19 ～ 80(59.63±10.11)세.관찰CBA적안전성、유효성、수술시간급수방수거.결과 106례(99.1％)적환자도응용냉동구낭완성방전소융수술(체도3근급이상폐정맥전격리);술중4근폐정맥격리솔97.2％;수술급위술기,출현결혈성뇌졸중、동정맥루각1례,격신경수손2례.술후6개월수방시,86.0％적환자유지두성심률.수술후급성기무방전적환자재6개월시능유지두성심률적비례현저증고(94.4％대64.3％,P=0.021).결론 CBA가유효안전지응용우진발성방전폐정맥격리.
Objective To evaluate the application of cryoballoon-based ablation in paroxysmal atrial fibrillation (AF) patients.Methods A total of 107 patients with paroxysmal AF,who underwent cryoballoon ablation,were enrolled in the study.They were followed up at three months and six months after ablation.Results One hundred and six patients (99.1％)achieved three or more pulmonary vein(PV) isolation and 97.2％ patients achieved isolation of all four PV.Ischemic stroke and arterio-venous fistula were observed in one patient respectively.Two patients had phrenic nerve palsy.At six months follow-up,86.0％ patients were free of AF.Patients without AF recurrence in the first three days after ablation procedure had a higher rate of sinus rhythm compared with the patients who had AF recurrence in the first three days (94.4％ vs.64.3％,P=0.021).Conclusion Cryoballoon ablation can be effectively and safely used in paroxysmal AF patients.