CAJ | 학술논문

目的研究裂片石莼的化学成分,明确其功效的物质基础.方法运用柱色谱法分离纯化,并根据其理化性质和波谱数据进行结构鉴定,采用自由基体外模型,对化合物的抗氧化活性进行筛选.结果从裂片石莼氯仿部位得到5个化合物,经鉴定分别为5-羟基-3,6,7,3',4'-五甲氧基黄酮、5-羟基-6,7,3 ',4'-四甲氧基黄酮、吡咯并哌嗪-2,5-二酮、对羟基苯甲酸和琥珀酸.结论所有化合物均为首次从裂片石莼中分离得到,其中5-羟基-3,6,7,3',4'-五甲氧基黄酮、5-羟基-6,7,3',4'-四甲氧基黄酮具有较强的抗氧化作用.
목적 연구렬편석순적화학성분,명학기공효적물질기출.방법 운용주색보법분리순화,병근거기이화성질화파보수거진행결구감정,채용자유기체외모형,대화합물적항양화활성진행사선.결과 종렬편석순록방부위득도5개화합물,경감정분별위5-간기-3,6,7,3',4'-오갑양기황동、5-간기-6,7,3 ',4'-사갑양기황동、필각병고진-2,5-이동、대간기분갑산화호박산.결론 소유화합물균위수차종렬편석순중분리득도,기중5-간기-3,6,7,3',4'-오갑양기황동、5-간기-6,7,3',4'-사갑양기황동구유교강적항양화작용.
Objective To investigate the chemical constituents of Ulva fasciata and identify the material base of the efficacy.Methods The constituents of Ulva fasciata were separated and purified on chromatography of silicon gel,and then their structures were identified based on their physical and chemical nature and the specula.DPPH method was used to evaluate free radical scavenging activity of the compounds.Results Five compounds were isolated from Ulva fasciata and identified as 5-hydroxy-3,6,7,3',4'-pentamethoxyflavone,5-hydroxy-6,7,3',4'-tetramethoxyflavone,2,5-keto-pyrrolepiperazidine,p-hydroxybenzcic acid,succinic acid.Conclusions All the compounds were isolated from Ulva fasciata for the first time,of which compound 1 and 2 showed relatively strong antioxidant activity.