CAJ | 학술논문

目的：探讨急诊应用胺碘酮治疗冠心病快速心律失常的临床疗效。方法随机抽取2012年10月~2014年10月我院收治的急诊冠心病快速心律失常患者120例，分为观察组与对照组，每组60例，给予对照组患者单纯胺碘酮口服治疗，给予观察组口服联合注射治疗，对比两组治疗后的疗效。结果观察组治疗有效率为95%，明显高于对照组的75.0%，差异明显（P＜0.05）；具有统计学意义；观察组不良反应6例、对照组8例，不良反应率方面差异不明显（P＞0.05），无统计学意义。结论胺碘酮口服联合注射治疗冠心病快速心律失常疗效显著，且具有很高的安全性，值得在临床治疗中推广使用。
목적：탐토급진응용알전동치료관심병쾌속심률실상적림상료효。방법수궤추취2012년10월~2014년10월아원수치적급진관심병쾌속심률실상환자120례，분위관찰조여대조조，매조60례，급여대조조환자단순알전동구복치료，급여관찰조구복연합주사치료，대비량조치료후적료효。결과관찰조치료유효솔위95%，명현고우대조조적75.0%，차이명현（P＜0.05）；구유통계학의의；관찰조불량반응6례、대조조8례，불량반응솔방면차이불명현（P＞0.05），무통계학의의。결론알전동구복연합주사치료관심병쾌속심률실상료효현저，차구유흔고적안전성，치득재림상치료중추엄사용。
Objective To investigate the clinical efficacy of amiodarone in coronary heart disease (CHD) patients with tachyarrhythmia in the emergency department. Methods A total of 120 CHD patients with tachyarrhythmia admitted to the emergency department of our hospital from October 2012 to October 2014 were randomly selected and divided into observation group (n=60) and control group (n=60). The control group was orally given amiodarone alone, while the observation group received oral amiodarone and amiodarone injection. The treatment outcomes of the two groups were compared. Results The observation group had a significantly higher response rate than the control group (95% vs 75%, P<0.05). Adverse reactions were seen in 6 cases in the observation group and in 8 cases in the control group, without significant difference in the incidence of adverse reactions (P>0.05). Conclusion Orally given and injected amiodarone has significant efficacy and high safety in CHD patients with tachyarrhythmia and holds promise for use in clinical treatment.