心血管病防治知识（下半月）
心血管病防治知識（下半月）
심혈관병방치지식（하반월）
XINXUEGUANBING FANGZHI ZHISHI
2015年
5期
51-53
,共3页
心肌梗死%浓度监测%临床诊断%应用价值
心肌梗死%濃度鑑測%臨床診斷%應用價值
심기경사%농도감측%림상진단%응용개치
Myocardial infarction%Concentration monitoring%Clinical diagnosis%Clinical value
目的：探讨在急性心肌梗死患者中，监测cTnI、CK-MB、Mb浓度对临床诊断的应用价值。方法选取我院收治的急性心肌梗死患者45例作为观察组，选择同期接受体检的健康人员45例作为对照组。采集受检人员静脉血液后，对血清进行cTnI、CK-MB、Mb指标监测，并对监测结果进行平行比较。结果观察组cTnI、CK-MB、Mb指标明显高于对照组，其中cTnI、CK-MB在发病后24h浓度最高，Mb在发病后6h后浓度最高，且cTnI、CK-MB监测的阳性率、准确性明显高于Mb，差异有统计学意义（P＜0.05）。结论和健康人群相比，急性心肌梗死患者的cTnI、CK-MB、Mb浓度明显增加，且cTnI、CK-MB监测准确率更高。因此进行指标监测，对于患者的病情诊断和发展具有重要的应用价值。
目的：探討在急性心肌梗死患者中，鑑測cTnI、CK-MB、Mb濃度對臨床診斷的應用價值。方法選取我院收治的急性心肌梗死患者45例作為觀察組，選擇同期接受體檢的健康人員45例作為對照組。採集受檢人員靜脈血液後，對血清進行cTnI、CK-MB、Mb指標鑑測，併對鑑測結果進行平行比較。結果觀察組cTnI、CK-MB、Mb指標明顯高于對照組，其中cTnI、CK-MB在髮病後24h濃度最高，Mb在髮病後6h後濃度最高，且cTnI、CK-MB鑑測的暘性率、準確性明顯高于Mb，差異有統計學意義（P＜0.05）。結論和健康人群相比，急性心肌梗死患者的cTnI、CK-MB、Mb濃度明顯增加，且cTnI、CK-MB鑑測準確率更高。因此進行指標鑑測，對于患者的病情診斷和髮展具有重要的應用價值。
목적：탐토재급성심기경사환자중，감측cTnI、CK-MB、Mb농도대림상진단적응용개치。방법선취아원수치적급성심기경사환자45례작위관찰조，선택동기접수체검적건강인원45례작위대조조。채집수검인원정맥혈액후，대혈청진행cTnI、CK-MB、Mb지표감측，병대감측결과진행평행비교。결과관찰조cTnI、CK-MB、Mb지표명현고우대조조，기중cTnI、CK-MB재발병후24h농도최고，Mb재발병후6h후농도최고，차cTnI、CK-MB감측적양성솔、준학성명현고우Mb，차이유통계학의의（P＜0.05）。결론화건강인군상비，급성심기경사환자적cTnI、CK-MB、Mb농도명현증가，차cTnI、CK-MB감측준학솔경고。인차진행지표감측，대우환자적병정진단화발전구유중요적응용개치。
Objective To explore the clinical values of concentration monitoring of cardiac troponin I (cTnI), creatine kinase-MB (CK-MB), and myoglobin (Mb) in the diagnosis of acute myocardial infarction (AMI). Methods A total of 45 patients with AMI in our hospital were selected in the observation group, and 45 healthy individuals who underwent physical examination during the same period were assigned to the control group. After venous blood was collected from each subject, serum levels of cTnI, CK-MB, and Mb were measured for monitoring and subsequent parallel comparison. Results Serum levels of cTnI, CK-MB, and Mb in AMI patients were significantly higher than those in controls. Serum cTnI and CK-MB reached peak levels at 24 h after the onset of AMI, and Mb reached peak concentration at 6 h after the onset of AMI. Furthermore, the positive rate and accuracy of cTnI and CK-MB were significantly higher than those of Mb. These differences were statistically significant (P<0.05). Conclusion Serum concentrations of cTnI, CK-MB, and Mb in AMI patients are significantly elevated compared with healthy population. Serum levels of cTnI and CK-MB have a higher accuracy in AMI monitoring. Monitoring of such parameters therefore has important clinical values in disease diagnosis and surveillance of disease progression.
