中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2015年
9期
1303-1305
,共3页
关节成形术,置换,髋%手术后出血%利伐沙班%低分子肝素
關節成形術,置換,髖%手術後齣血%利伐沙班%低分子肝素
관절성형술,치환,관%수술후출혈%리벌사반%저분자간소
Arthroplasty,Replacement,Hip%Postoperative Hemorrhage%Rivaroxaban%Low Molecular Weight Heparin
目的 探讨利伐沙班与低分子肝素对初次单侧人工半髋置换术后隐性失血的影响.方法 收集因股骨颈骨折行单侧人工半髋置换术老年患者共80例,术后按随机数字表法分为利伐沙班组40例和低分子肝素组40例.两组均在术后12 h开始每天分别口服利伐沙班10 mg和皮下注射低分子肝素5000u,比较两组围手术期实际失血总量、显性失血量、隐性失血量及隐性失血量占实际失血总量百分比;并记录35 d内出血事件.结果 利伐沙班组实际失血总量、显性失血量、隐性失血、隐性失血量占实际失血总量百分比分别为(671.00±55.61) mL、(313.88±14.53)mL、(350.00±29.41)mL、(52.00±5.22)％,低分子肝素组分别为(662.00±30.19)mL、(288.87±15.33) mL、(372.00±35.10)mL、(56.00±6.71)％,两组差异均无统计学意义(t =0.93、0.93、0.83、1.03,均P＞0.05).结论 对于初次行单侧人工半髋置换术的患者,围手术期使用利伐沙班与低分子肝素后隐性出血风险及出血事件发生率无明显差异.
目的 探討利伐沙班與低分子肝素對初次單側人工半髖置換術後隱性失血的影響.方法 收集因股骨頸骨摺行單側人工半髖置換術老年患者共80例,術後按隨機數字錶法分為利伐沙班組40例和低分子肝素組40例.兩組均在術後12 h開始每天分彆口服利伐沙班10 mg和皮下註射低分子肝素5000u,比較兩組圍手術期實際失血總量、顯性失血量、隱性失血量及隱性失血量佔實際失血總量百分比;併記錄35 d內齣血事件.結果 利伐沙班組實際失血總量、顯性失血量、隱性失血、隱性失血量佔實際失血總量百分比分彆為(671.00±55.61) mL、(313.88±14.53)mL、(350.00±29.41)mL、(52.00±5.22)％,低分子肝素組分彆為(662.00±30.19)mL、(288.87±15.33) mL、(372.00±35.10)mL、(56.00±6.71)％,兩組差異均無統計學意義(t =0.93、0.93、0.83、1.03,均P＞0.05).結論 對于初次行單側人工半髖置換術的患者,圍手術期使用利伐沙班與低分子肝素後隱性齣血風險及齣血事件髮生率無明顯差異.
목적 탐토리벌사반여저분자간소대초차단측인공반관치환술후은성실혈적영향.방법 수집인고골경골절행단측인공반관치환술노년환자공80례,술후안수궤수자표법분위리벌사반조40례화저분자간소조40례.량조균재술후12 h개시매천분별구복리벌사반10 mg화피하주사저분자간소5000u,비교량조위수술기실제실혈총량、현성실혈량、은성실혈량급은성실혈량점실제실혈총량백분비;병기록35 d내출혈사건.결과 리벌사반조실제실혈총량、현성실혈량、은성실혈、은성실혈량점실제실혈총량백분비분별위(671.00±55.61) mL、(313.88±14.53)mL、(350.00±29.41)mL、(52.00±5.22)％,저분자간소조분별위(662.00±30.19)mL、(288.87±15.33) mL、(372.00±35.10)mL、(56.00±6.71)％,량조차이균무통계학의의(t =0.93、0.93、0.83、1.03,균P＞0.05).결론 대우초차행단측인공반관치환술적환자,위수술기사용리벌사반여저분자간소후은성출혈풍험급출혈사건발생솔무명현차이.
Objective To investigate the impact of rivaroxaban and low molecular weight heparin on hidden blood loss after unilateral first half artificial hip replacement surgery.Methods According to the digital table,a total of 80 cases because of femoral neck fractures in elderly patients with unilateral arthroplasty artificial hip and a half after surgery were randomly divided into the rivaroxaban group and low molecular weight heparin (LMWH) group,40 cases in each group.In both groups,respectively,after 12 h begin daily oral rivaroxaban 10 mg and subcutaneous low molecular weight heparin 5 000 u,compared the two groups around the actual amount of perioperative blood loss,blood loss was dominant,recessive blood loss and hidden blood loss accounts,the actual percentage of total blood loss,and recorded 35d bleeding events.Results The total amount of blood loss,dominant blood loss,hidden blood loss and the hidden blood loss accounted for the actual percentage of the total amount of blood loss of the rivaroxaban group were (671.00 ± 55.61) mL,(313.88 ± 14.53) mL,(350.00 ± 29.41) mL,(52.00 ± 5.22) ％,respectively,which of the the LMWH group were (662.00 ± 30.19) mL,(288.87 ± 15.33) mL,(372.00 ± 35.10) mL,(56.00 ± 6.71) ％,there were no significant differences between the two groups (t =0.93,0.93,0.83,1.03,all P ＞ 0.05).Conclusion For patients first underwent unilateral hip replacement surgery artificial half,perioperative using rivaroxaban or LMWH has no significantly differences in hidden risk of bleeding and bleeding event rate.
