临床荟萃
臨床薈萃
림상회췌
CLINICAL FOCUS
2015年
6期
637-640
,共4页
孤立性肺结节%体层摄影术,发射型计算机%辐射剂量%成像,三维
孤立性肺結節%體層攝影術,髮射型計算機%輻射劑量%成像,三維
고립성폐결절%체층섭영술,발사형계산궤%복사제량%성상,삼유
solitary pulmonary nodule%tomography,emission-computed%radiation dosage%imaging,three-dimensional
目的：探讨超低剂量 CT 在体检人群中肺结节体积随诊中的应用价值。方法行常规剂量胸部 CT 扫描遵医嘱半年后复查的125例体检者共145例实性结节,同时行50 mAs 和25 mAs 低剂量与超低剂量2次胸部 CT扫描所获得的影像资料进行分析。结节体积应用 GE4.4后处理工作站三维体积测量软件(advanced lung analysis, ALA)自动进行测量。计算2次测量的相对体积差值(relative volume difference,RVD),RVD≤10%为体积测量满意, RVD>10%为体积测量不满意。结果145例结节2次体积测量的满意度为77.9%,相关系数 r 为0.997,体积测量差异无统计学意义(P >0.05)；Bland-Altman 散点图 RVD 的95%可信区间为-0.13~0.15,2次体积测量总体趋于一致。两样本 t 检验显示毛刺型结节及组织旁型结节 RVD 不满意率较其他类型结节明显增高。结论超低剂量 CT相对于低剂量 CT 三维体积测量具有较高的一致性,可用于肺结节的体积随诊工作中。而对于毛刺型结节及胸膜旁型结节,我们建议采用常规低剂量 CT 进行随访观察。
目的：探討超低劑量 CT 在體檢人群中肺結節體積隨診中的應用價值。方法行常規劑量胸部 CT 掃描遵醫囑半年後複查的125例體檢者共145例實性結節,同時行50 mAs 和25 mAs 低劑量與超低劑量2次胸部 CT掃描所穫得的影像資料進行分析。結節體積應用 GE4.4後處理工作站三維體積測量軟件(advanced lung analysis, ALA)自動進行測量。計算2次測量的相對體積差值(relative volume difference,RVD),RVD≤10%為體積測量滿意, RVD>10%為體積測量不滿意。結果145例結節2次體積測量的滿意度為77.9%,相關繫數 r 為0.997,體積測量差異無統計學意義(P >0.05)；Bland-Altman 散點圖 RVD 的95%可信區間為-0.13~0.15,2次體積測量總體趨于一緻。兩樣本 t 檢驗顯示毛刺型結節及組織徬型結節 RVD 不滿意率較其他類型結節明顯增高。結論超低劑量 CT相對于低劑量 CT 三維體積測量具有較高的一緻性,可用于肺結節的體積隨診工作中。而對于毛刺型結節及胸膜徬型結節,我們建議採用常規低劑量 CT 進行隨訪觀察。
목적：탐토초저제량 CT 재체검인군중폐결절체적수진중적응용개치。방법행상규제량흉부 CT 소묘준의촉반년후복사적125례체검자공145례실성결절,동시행50 mAs 화25 mAs 저제량여초저제량2차흉부 CT소묘소획득적영상자료진행분석。결절체적응용 GE4.4후처리공작참삼유체적측량연건(advanced lung analysis, ALA)자동진행측량。계산2차측량적상대체적차치(relative volume difference,RVD),RVD≤10%위체적측량만의, RVD>10%위체적측량불만의。결과145례결절2차체적측량적만의도위77.9%,상관계수 r 위0.997,체적측량차이무통계학의의(P >0.05)；Bland-Altman 산점도 RVD 적95%가신구간위-0.13~0.15,2차체적측량총체추우일치。량양본 t 검험현시모자형결절급조직방형결절 RVD 불만의솔교기타류형결절명현증고。결론초저제량 CT상대우저제량 CT 삼유체적측량구유교고적일치성,가용우폐결절적체적수진공작중。이대우모자형결절급흉막방형결절,아문건의채용상규저제량 CT 진행수방관찰。
Objective To evaluate the application value of ultra low dose CT with three-dimensional volumetric measurement in follow-up physical examination population with solid pulmonary nodules.Methods The study was performed on the data of 145 solid nodules in 125 patients who had undergone a standard-dose chest CT scan and had a follow-up 25mAs and 50mAs CT simultaneously.The volume of pulmonary nodules was measured using advanced lung analysis software.The level of agreement was expressed using the relative volume differences.Results The ratio of satisficing segmentation was 77.9% for 145 nodules.Spearman correlation efficient between two conditions was highly correlated (r =0.997).The repeated measurements did not result in significant difference (P >0.05).Bland-Altman scatter diagram revealed that 95% CI of RVD was -0.13-0.1 5.Two paired samples T test showed that spiculated and pleura-attached nodules had significantly high ratio of unsatisfied segmentation respectively.Conclusion Three-dimensional measurement of ultra low dose CT shows high consistency and can be used for daily follow-up work of pulmonary nodules.However,a routine low dose was advised for spiculated and pleura-attached nodules.
