CAJ | 학술논문

目的：探讨超声检查对甲状腺良、恶性肿瘤的诊断及甲状腺生化指标与肿瘤良恶性的关系，以提高甲状腺癌的诊断准确性。方法收集360例甲状腺肿瘤患者的临床资料，分析超声对甲状腺肿瘤良恶性的诊断准确性及甲状腺TSH、TgAb、TPOAb生化指标在良恶性结节组之间的差异。结果甲状腺恶性结节内的微钙化（63/120，52.5%）比例明显高于良性结节组（11/240，4.6%），组间比较差异具有统计学意义（P<0.05）。甲状腺恶性结节组术前血清TSH、TgAb、TPOAb水平明显高于良性结节组，差异具有统计学意义（P<0.05），且TSH浓度区间越高的组别，甲状腺癌的发病率越高（P<0.05）。结论术前超声检查及患者血清TSH、TgAb、TPOAb水平可作为预测甲状腺肿瘤良恶性的重要指标。
목적：탐토초성검사대갑상선량、악성종류적진단급갑상선생화지표여종류량악성적관계，이제고갑상선암적진단준학성。방법수집360례갑상선종류환자적림상자료，분석초성대갑상선종류량악성적진단준학성급갑상선TSH、TgAb、TPOAb생화지표재량악성결절조지간적차이。결과갑상선악성결절내적미개화（63/120，52.5%）비례명현고우량성결절조（11/240，4.6%），조간비교차이구유통계학의의（P<0.05）。갑상선악성결절조술전혈청TSH、TgAb、TPOAb수평명현고우량성결절조，차이구유통계학의의（P<0.05），차TSH농도구간월고적조별，갑상선암적발병솔월고（P<0.05）。결론술전초성검사급환자혈청TSH、TgAb、TPOAb수평가작위예측갑상선종류량악성적중요지표。
Objective To investigate ultrasonography in the diagnosis of benign or malignant thyroid tumors and the as-sociation between biochemical indexes and thyroid tumors with benign or malignant characteristic ,to improve the diagnostic ac-curacy of thyroid carcinoma. Methods Collected the clinical data of 360 patients with thyroid tumors,analyzed the accuracy of ultrasound in the diagnosis of benign or malignant thyroid tumor and the difference of TSH,TgAb,TPOAb in thyroid biochem-ical indexes between benign and malignant thyroid tumor. Results Proportion of microcalcification in malignant thyroid nod-ules group(63/120,52.5%) was significantly higher than that in benign nodules group (11/240,4.6%),the difference was statis-tically significant(P<0.05). The preoperative serum TSH,TgAb,TPOAb level in malignant thyroid nodules group was significant-ly higher than that in benign nodules group,the difference was statistically significant (P<0.05). The higher TSH concentration range of the group was,the higher incidence rate of thyroid cancer was(P<0.05). Conclusion Ultrasonography and preopera-tive serum TSH,TgAb,TPOAb levels can be used as important indicators to predict benign or malignant thyroid carcinoma.