CAJ | 학술논문

雌激素受体（ERα）是一种蛋白质分子，作用是与雌激素结合成为激素-受体复合物，使雌激素发挥生物学效应。作为配体活化转录因子的核受体家族成员之一，雌激素参与靶细胞的增殖与分化。经过多年的研究调查显示：雌激素受体的功能受很多因素的影响，主要是因子的调节。它还与很多疾病有着密切关系。该文旨在介绍与其有关的几类调节因子与相关的疾病以及环境对其的影响。
자격소수체（ERα）시일충단백질분자，작용시여자격소결합성위격소-수체복합물，사자격소발휘생물학효응。작위배체활화전록인자적핵수체가족성원지일，자격소삼여파세포적증식여분화。경과다년적연구조사현시：자격소수체적공능수흔다인소적영향，주요시인자적조절。타환여흔다질병유착밀절관계。해문지재개소여기유관적궤류조절인자여상관적질병이급배경대기적영향。
Estrogen receptor-α (ER alpha) is a kind of protein molecule, the role is in combination with estrogen become estrogen receptor complexes, making estrogen produce biological effect. As a member of the nuclear receptor family of ligands activation of transcription factors, estrogen take part in the proliferation and differentiation of target cell. After years of research shows that: the function of the estrogen receptor is affected by many factors, mainly is the adjustment factor. It also has close relationship with many diseases. This paper aims to introduce its associated with related types of regulating factor and the influence of environment on the disease.