CAJ | 학술논문

目的：探讨注射用生长抑素对腹腔镜手术治疗粘连性肠梗阻疗效的影响。方法选择浙江省苍南县第二人民医院2013年1月～2014年5月收治粘连性肠梗阻患者80例，随机分为对照组和观察组，每组各40例；对照组：采用腹腔镜手术治疗，同时从患者入院后予以基础治疗；观察组：在对照组治疗的基础上予以生长抑素注射液。观察比较2组患者的治疗效果、胃肠减压引流量、肛门恢复排气时间、中转外科手术率、住院时间、术后镇痛数、术后并发症、随访观察治疗后1年内的复发率，并应用EORTC生命质量功能评分对2组患者术后生活质量进行评价。结果治疗后，对照组总有效率为85．00％，观察组总有效率为92．50％，2组比较差异无统计学意义（χ2＝2．635）；观察组患者胃肠减压量、肠蠕动恢复时间、肛门恢复排气时间、住院时间和中转外科手术率均显著少于对照组（P均＜0．01）；通过对2组患者EORTC生命质量测量评分比较，观察组显著高于对照组，差异有统计学意义（P均＜0．01）。2组手术成功率均为100％，观察组术后镇痛数、随访1年的复发率均显著低于对照组（ P＜0．01）；观察组并发症与对照组比较差异无统计学意义（χ2＝2．813）。结论腹腔镜手术治疗粘连性肠梗阻的同时，给予生长抑素可以提高临床疗效，缩短患者恢复时间，降低复发率，提高生存治疗。
목적：탐토주사용생장억소대복강경수술치료점련성장경조료효적영향。방법선택절강성창남현제이인민의원2013년1월～2014년5월수치점련성장경조환자80례，수궤분위대조조화관찰조，매조각40례；대조조：채용복강경수술치료，동시종환자입원후여이기출치료；관찰조：재대조조치료적기출상여이생장억소주사액。관찰비교2조환자적치료효과、위장감압인류량、항문회복배기시간、중전외과수술솔、주원시간、술후진통수、술후병발증、수방관찰치료후1년내적복발솔，병응용EORTC생명질량공능평분대2조환자술후생활질량진행평개。결과치료후，대조조총유효솔위85．00％，관찰조총유효솔위92．50％，2조비교차이무통계학의의（χ2＝2．635）；관찰조환자위장감압량、장연동회복시간、항문회복배기시간、주원시간화중전외과수술솔균현저소우대조조（P균＜0．01）；통과대2조환자EORTC생명질량측량평분비교，관찰조현저고우대조조，차이유통계학의의（P균＜0．01）。2조수술성공솔균위100％，관찰조술후진통수、수방1년적복발솔균현저저우대조조（ P＜0．01）；관찰조병발증여대조조비교차이무통계학의의（χ2＝2．813）。결론복강경수술치료점련성장경조적동시，급여생장억소가이제고림상료효，축단환자회복시간，강저복발솔，제고생존치료。
Objective To investigate somatostatin effect of on curative effect of laparoscopic operation in treatment of adhesive intestinal obstruction.Methods 80 patients with adhesive intestinal obstruction from January 2013 to May 2014, were randomly divided into control group and observation group, 40 cases in each group; the control group: treated with laparoscopic operation at the same time, from the patients admitted to the hospital after the foundation treatment; the observation group: somatostatin injection based on the treatment in control group.To observe the therapeutic effect of two groups, gastrointestinal decompression drainage, anal exhaust time, hospitalization time, the rate of conversion to surgical operation, postoperative analgesia, postoperative complications, follow-up treatment within 1 years after the recurrence rate, and application of functional EORTC life quality evaluation of the quality of life of two groups of patients with postoperative score.Results After treatment, the total effective rate of control group was 85%, the total efficiency of observation group was 92.50%, but the difference was not statistically significant (χ2 =2.635).After treatment, patients in observation group,the amount of gastrointestinal decompression, intestinal peristalsis recovery time, anal exhaust time, hospitalization time surgical operation and transfer rate were significantly lower than control group (P<0.01).By measuring the quality of life of EORTC scores between two groups, the observation group was significantly higher than the control group, there was significant difference ( P <0.01 ) .The success rate of the operation of the two groups was 100%, the observation group recurrence after 1 years of follow-up, the number of analgesic were significantly lower than the control group, there were significant differences.Complications in the observation group compared with the control group, the difference was not statistically significant (χ2 =2.813).Conclusion Laparoscopic operation in treatment of adhesive intestinal obstruction, given somatostatin can improve the clinical curative effect, shorten the recovery time of patients, reduce the recurrence rate, improve the survival of treatment.