中国生化药物杂志
中國生化藥物雜誌
중국생화약물잡지
CHINESE JOURNAL OF BIOCHEMICAL PHARMACEUTICS
2015年
5期
181-185
,共5页
抗菌肽%来源%功能%机制%应用前景
抗菌肽%來源%功能%機製%應用前景
항균태%래원%공능%궤제%응용전경
antimicrobial peptides%origins%action%mechanism%application prospects
抗菌肽( antimicrobial peptides, AMPs)是自然界生物体内非常重要的防御体系,能够对抗细菌、真菌、病毒甚至肿瘤细胞。抗菌肽具有广谱抗菌活性,且不易产生耐药性,这使得抗菌肽成为应用前景非常广阔的抑菌剂。本文综述了抗菌肽的来源、功能及其作用机制,并对其应用前景进行展望。
抗菌肽( antimicrobial peptides, AMPs)是自然界生物體內非常重要的防禦體繫,能夠對抗細菌、真菌、病毒甚至腫瘤細胞。抗菌肽具有廣譜抗菌活性,且不易產生耐藥性,這使得抗菌肽成為應用前景非常廣闊的抑菌劑。本文綜述瞭抗菌肽的來源、功能及其作用機製,併對其應用前景進行展望。
항균태( antimicrobial peptides, AMPs)시자연계생물체내비상중요적방어체계,능구대항세균、진균、병독심지종류세포。항균태구유엄보항균활성,차불역산생내약성,저사득항균태성위응용전경비상엄활적억균제。본문종술료항균태적래원、공능급기작용궤제,병대기응용전경진행전망。
Antimicrobial peptides ( AMPs) are critical component of the innate immune system of organisms, and have been demonstrated with the activity against a variety of microorganisms including bacteria, yeast, fungi, viruses and even tumor cells.Broad-spectrum activity and low propensity for resistance development make the AMPs as a kind of great potential for development of new anti-infective agents.In this paper, the origins, the action, the mechanism, the application prospects are reviewed.