CAJ | 학술논문

目的：探讨对临床确诊为支气管结核病的患者采用纤支镜导管介入给药的方式治疗的临床疗效。方法随机选取2013年4月—2014年6月因患有支气管结核于该所住院部采用纤支镜导管介入给药进行治疗的30例患者为观察组，同期采用单纯药物治疗的30例患者为对照组，对比两组患者的治疗效果。结果在两组患者的治疗过程中，观察组患者的治疗的总有效率明显优于对照组，差异有统计学意义(P<0.05)，在疾病的转归方面，两组患者在治疗前后的肺不张出现率方面无明显差异，差异无统计学意义(P>0.05)，但是在治疗后肺不张的改善情况的比较中，观察组具有明显优势，差异有统计学意义(P<0.05)；在致病菌的研究方面，两组患者在治疗前和治疗后2周的比较中，转阴率无明显差异，差异无统计学意义(P>0.05)；观察组患者在治疗1个疗程后的转阴率明显优于对照组，差异有统计学意义(P<0.05)。结论因采用纤支镜导管介入给药的过程中，疗效明显，致病菌的转阴情况具有明显优势，同时对病情的控制效果客观，值得在临床上推广。
목적：탐토대림상학진위지기관결핵병적환자채용섬지경도관개입급약적방식치료적림상료효。방법수궤선취2013년4월—2014년6월인환유지기관결핵우해소주원부채용섬지경도관개입급약진행치료적30례환자위관찰조，동기채용단순약물치료적30례환자위대조조，대비량조환자적치료효과。결과재량조환자적치료과정중，관찰조환자적치료적총유효솔명현우우대조조，차이유통계학의의(P<0.05)，재질병적전귀방면，량조환자재치료전후적폐불장출현솔방면무명현차이，차이무통계학의의(P>0.05)，단시재치료후폐불장적개선정황적비교중，관찰조구유명현우세，차이유통계학의의(P<0.05)；재치병균적연구방면，량조환자재치료전화치료후2주적비교중，전음솔무명현차이，차이무통계학의의(P>0.05)；관찰조환자재치료1개료정후적전음솔명현우우대조조，차이유통계학의의(P<0.05)。결론인채용섬지경도관개입급약적과정중，료효명현，치병균적전음정황구유명현우세，동시대병정적공제효과객관，치득재림상상추엄。
Objective To concentratedly investigate the clinical effect of bronchofiberscope interventional administration on patients diagnosed with bronchial tuberculosis confirmedly.Methods 30 cases with bronchial tuberculosis treated by bronchofiberscope interventional administration and other 30 cases with bronchial tuberculosis treated by simple medication in our hospital from April 2013 to June 2014 were selected as the observation group and the control group. And the treatment effect was compared between the two groups.Results During the treatment, the overall response rate of the observation group was much higher than that of the control group, the difference was statistically significant difference(<0.05). Before treatment, there was no obvious difference in the incidence of atelectasis between the two groups(>0.05), but after treatment, compared with the control group, the improvement of atelectasis in the observation group was much better with statistically significant difference(<0.05). In the study of pathogenic bacteria, before treatment and 2 weeks after treatment, there was no obvious difference in the rate of patients whose outcome turns to negative between the two groups, with no statistically significant difference(>0.05); the observation group was significantly better than the control group in the negative conversion rate after 1 course of treatment, with statistically significant difference(P<0.05).Conclusion Bronchofiberscope interventional administration is worth promoting in clinical practice because it has obvious advantages on the negative conversion situation of pathogenic bacteria and can control illness condition well.