中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
14期
117-119
,共3页
中老年%神经节苷脂钠%综合疗法%神经功能
中老年%神經節苷脂鈉%綜閤療法%神經功能
중노년%신경절감지납%종합요법%신경공능
Middle and old age%Ganglioside sodium%Comprehensive therapy%Neurological function
目的：探讨神经节苷脂钠对中老年脑卒中患者神经功能预后的影响。方法选取本院神经内科2012年7月~2013年6月收治的43例脑卒中患者作为对照组，给予常规综合疗法治疗。选取本院神经内科2013年7月~2014年6月收治的43例脑卒中患者作为研究组，在对照组的基础上给予神经节苷脂钠治疗。比较两组治疗前后的血流动力学指标、氧化应激状况及神经功能缺损评分。结果研究组治疗后15、30、60 d的神经功能缺损程度评分显著低于对照组，差异有统计学意义(P<0.05)。研究组的临床总有效率为90.7%，显著高于对照组的62.8%，差异有统计学意义(P<0.05)。结论神经节苷脂钠联合综合疗法治疗中老年脑卒中效果显著，能够促进神经功能修复，值得临床推广应用。
目的：探討神經節苷脂鈉對中老年腦卒中患者神經功能預後的影響。方法選取本院神經內科2012年7月~2013年6月收治的43例腦卒中患者作為對照組，給予常規綜閤療法治療。選取本院神經內科2013年7月~2014年6月收治的43例腦卒中患者作為研究組，在對照組的基礎上給予神經節苷脂鈉治療。比較兩組治療前後的血流動力學指標、氧化應激狀況及神經功能缺損評分。結果研究組治療後15、30、60 d的神經功能缺損程度評分顯著低于對照組，差異有統計學意義(P<0.05)。研究組的臨床總有效率為90.7%，顯著高于對照組的62.8%，差異有統計學意義(P<0.05)。結論神經節苷脂鈉聯閤綜閤療法治療中老年腦卒中效果顯著，能夠促進神經功能脩複，值得臨床推廣應用。
목적：탐토신경절감지납대중노년뇌졸중환자신경공능예후적영향。방법선취본원신경내과2012년7월~2013년6월수치적43례뇌졸중환자작위대조조，급여상규종합요법치료。선취본원신경내과2013년7월~2014년6월수치적43례뇌졸중환자작위연구조，재대조조적기출상급여신경절감지납치료。비교량조치료전후적혈류동역학지표、양화응격상황급신경공능결손평분。결과연구조치료후15、30、60 d적신경공능결손정도평분현저저우대조조，차이유통계학의의(P<0.05)。연구조적림상총유효솔위90.7%，현저고우대조조적62.8%，차이유통계학의의(P<0.05)。결론신경절감지납연합종합요법치료중노년뇌졸중효과현저，능구촉진신경공능수복，치득림상추엄응용。
Objective To explore the influence of ganglioside sodium on the prognosis of neurological function for mid-dle-aged and elderly patients with cerebral apoplexy. Methods 43 patients with cerebral apoplexy in the department of neurology in our hospital from July 2012 to June 2013 were selected as the control group,which was given regular com-prehensive therapy.43 patients with cerebral apoplexy in the department of neurology in our hospital from July 2013 to June 2014 were selected as the research group,which was given ganglioside sodium on the basis of the control group. Hemodynamic index,oxidative stress status and the score of deficiency of neurological function before and after treat-ment in two groups was compared. Results The score of deficiency of neurological function at 15,30 and 60 days after treatment in the research group were lower than that in the control group,with significant difference (P<0.05).The total clinical effective rate in the research group was 90.7%,which was higher than 62.8% in the control group,with signifi-cant difference (P<0.05). Conclusion The effect of ganglioside sodium combined with comprehensive therapy in the treatment of cerebral apoplexy in middle-aged and elderly patient is significant,which can promote the recovery of neu-rological function,it is worthy of clinical promotion and application.
