中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
14期
105-107
,共3页
李文兵%李安学%蔡云亮%朱红
李文兵%李安學%蔡雲亮%硃紅
리문병%리안학%채운량%주홍
地佐辛%麻醉%躁动%应激反应%不良反应
地佐辛%痳醉%躁動%應激反應%不良反應
지좌신%마취%조동%응격반응%불량반응
Dezocine%Anesthesia%Dysphoria%Stress response%Adverse effect
目的:分析地佐辛术前给药对全身麻醉患者苏醒期躁动和应激反应的影响。方法随机抽取本院2012年3月~2014年3月收治的择期接受腹腔镜手术治疗的80例患者作为研究对象,按照随机对照法将其分为对照组与观察组,每组40例。观察组给予地佐辛术前给药,对照组术前给予生理盐水,采取躁动评分及镇静评分量表评估两组患者苏醒期躁动及应激反应发生情况,记录患者的苏醒时间。结果观察组躁动评级玉级38例,Ⅱ级2例,躁动发生率为5.0%,明显低于对照组的35.0%(P<0.05)。观察组的苏醒时间为(10.2±2.5)min,拔管时间为(13.2±3.4)min,均短于对照组,且观察组的镇静评分为(2.7±0.2)分,明显高于对照组,疼痛评分为(1.4±0.3)分,显著低于对照组(P<0.05)。拔管时,观察组的MAP为(86.0±13.3)mm Hg,血压稳定情况明显优于对照组,且其心率为(78.0±11.3)/min,稳定情况优于对照组(P<0.05)。结论采用地佐辛术前镇痛处理方案可降低拔管期患者躁动发生率,降低术后不良反应发生率,镇痛效果佳,安全性高,值得推广应用。
目的:分析地佐辛術前給藥對全身痳醉患者囌醒期躁動和應激反應的影響。方法隨機抽取本院2012年3月~2014年3月收治的擇期接受腹腔鏡手術治療的80例患者作為研究對象,按照隨機對照法將其分為對照組與觀察組,每組40例。觀察組給予地佐辛術前給藥,對照組術前給予生理鹽水,採取躁動評分及鎮靜評分量錶評估兩組患者囌醒期躁動及應激反應髮生情況,記錄患者的囌醒時間。結果觀察組躁動評級玉級38例,Ⅱ級2例,躁動髮生率為5.0%,明顯低于對照組的35.0%(P<0.05)。觀察組的囌醒時間為(10.2±2.5)min,拔管時間為(13.2±3.4)min,均短于對照組,且觀察組的鎮靜評分為(2.7±0.2)分,明顯高于對照組,疼痛評分為(1.4±0.3)分,顯著低于對照組(P<0.05)。拔管時,觀察組的MAP為(86.0±13.3)mm Hg,血壓穩定情況明顯優于對照組,且其心率為(78.0±11.3)/min,穩定情況優于對照組(P<0.05)。結論採用地佐辛術前鎮痛處理方案可降低拔管期患者躁動髮生率,降低術後不良反應髮生率,鎮痛效果佳,安全性高,值得推廣應用。
목적:분석지좌신술전급약대전신마취환자소성기조동화응격반응적영향。방법수궤추취본원2012년3월~2014년3월수치적택기접수복강경수술치료적80례환자작위연구대상,안조수궤대조법장기분위대조조여관찰조,매조40례。관찰조급여지좌신술전급약,대조조술전급여생리염수,채취조동평분급진정평분량표평고량조환자소성기조동급응격반응발생정황,기록환자적소성시간。결과관찰조조동평급옥급38례,Ⅱ급2례,조동발생솔위5.0%,명현저우대조조적35.0%(P<0.05)。관찰조적소성시간위(10.2±2.5)min,발관시간위(13.2±3.4)min,균단우대조조,차관찰조적진정평분위(2.7±0.2)분,명현고우대조조,동통평분위(1.4±0.3)분,현저저우대조조(P<0.05)。발관시,관찰조적MAP위(86.0±13.3)mm Hg,혈압은정정황명현우우대조조,차기심솔위(78.0±11.3)/min,은정정황우우대조조(P<0.05)。결론채용지좌신술전진통처리방안가강저발관기환자조동발생솔,강저술후불량반응발생솔,진통효과가,안전성고,치득추엄응용。
Objective To analyze the impact of pre-operative administration of dezocine on emergence agitation and stress response for patients under general anesthesia. Methods 80 patients received selective laparoscopic surgery admitted into our hospital from March 2012 to March 2014 were randomly selected as research subjects.They were randomly divided into control group (n=40) and observation group (n=40) according to the randomized control method. Observation group was given pre-operative dezocine,and control group was given saline before surgery.Sedation and agitation score scale was applied to evaluate condition of emergence agitation and stress response in two groups,and patients’ recovery time was recorded. Results In observation group,38 patients were rated agitation level Ⅰ,and 2 patients were rated level II.The incidence rate of agitation (5.0%) was significantly lower than that of in control group (35.0%) (P<0.05);the emergence time in observation group [ (10.2±2.5) min]and extubating time [ (13.2±3.4) min] was shorter than that of control group respectively.Sedation score in observation group [(2.7±0.2) points] was significantly higher than that in control group.Pain score in observation group [ (1.4±0.3) points] was significantly lower than that in control group (P<0.05).Upon extubating,MAP in observation group was (86.0±13.3) mm Hg,and the blood pressure stability was significantly better than that in control group ahile the heart rate in observation group was (78.0±11.3) times every minute,and the stability of heart rate was also better than that in control group (P<0.05). Conclusion Pre-operative analgesia treatment scheme of dezocine before surgery helps reduce the incidence rate of agitation during extubating period in patients and lower the incidence rate of adverse effect.It has a favorable effect of analgesia and high safety, which is worthy of promotion and application.