CAJ | 학술논문

目的：分析由金黄色葡萄球菌导致的医院感染的临床特点和耐药特征。方法分析导致该院67例患者发生医院感染的危险因素及耐药特点，采用全自动细菌鉴定仪对分离的金黄色葡萄球菌菌株进行鉴定，采用纸片扩散法（K-B法）进行药物敏感性试验。结果67例医院感染患者共分离出75株金黄色葡萄球菌，其中包括61株耐甲氧西林金黄色葡萄球菌和14株甲氧西林敏感金黄色葡萄球菌。耐甲氧西林金黄色葡萄球菌的耐药性明显高于甲氧西林敏感金黄色葡萄球菌（P<0.05）。67例患者均存在严重的基础疾病，其中59例患者临床治疗接受过侵入性操作，发生感染的部位主要为肺部。结论金黄色葡萄球菌医院感染的发病群体主要为病情严重，接受过侵入性操作治疗的患者，感染部位主要为肺部，耐甲氧西林金黄色葡萄球菌对对数抗菌药物具有高耐药性。
목적：분석유금황색포도구균도치적의원감염적림상특점화내약특정。방법분석도치해원67례환자발생의원감염적위험인소급내약특점，채용전자동세균감정의대분리적금황색포도구균균주진행감정，채용지편확산법（K-B법）진행약물민감성시험。결과67례의원감염환자공분리출75주금황색포도구균，기중포괄61주내갑양서림금황색포도구균화14주갑양서림민감금황색포도구균。내갑양서림금황색포도구균적내약성명현고우갑양서림민감금황색포도구균（P<0.05）。67례환자균존재엄중적기출질병，기중59례환자림상치료접수과침입성조작，발생감염적부위주요위폐부。결론금황색포도구균의원감염적발병군체주요위병정엄중，접수과침입성조작치료적환자，감염부위주요위폐부，내갑양서림금황색포도구균대대수항균약물구유고내약성。
Objective To analyze the clinical characteristics of nosocomial infections caused by Staphylococcus aureus and the resistance characteristics of Staphylococcus aureus.Methods The resistance characteristics of Staphylococcus aureus and the risk factors that caused the nosocomial infections in 67 patients of our hospital were analyzed. The automated bacterial identification system was used to identify separated Staphylococcus aureus strains. Drug sensitivity test was conducted by disk diffusion technique (K-B method).Results 75 Staphylococcus aureus were separated from 67 patients with nosocomial infections, including 61 methicillin-resistant Staphylococcus aureus and 14 methicillin-sensitive Staphylococcus aureus. Resistance of methicillin-resistant Staphylococcus aureus was significantly higher than that of methicillin-sensitive Staphylococcus aureus (P <0.05). Underlying diseases were found in 67 patients , among them, 59 patients with Pulmonary infection had received invasive operation during clinical treatment. Conclusion Nosocomial infection caused by Staphylococcus Aureus usually occurs in patients who have received treatment containing invasive procedures and who are suffering from Pulmonary infection, and the resistance of methicillin-resistant Staphylococcus aureus was much higher.