中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
11期
44-45
,共2页
蒋明%高小盼%陆晓%来凤勇
蔣明%高小盼%陸曉%來鳳勇
장명%고소반%륙효%래봉용
介入化疗栓塞%腹部热疗%晚期%胃癌
介入化療栓塞%腹部熱療%晚期%胃癌
개입화료전새%복부열료%만기%위암
Interventional chemotherapy embolization%Abdominal thermotherapy%Advanced%Gastric cancer
目的：探讨介入化疗栓塞联合腹部热疗治疗晚期胃癌的近远期疗效。方法选取该院收治的129例晚期胃癌患者为研究对象,根据其意愿分成A、B、C3组，A、B组均予以介入化疗栓塞方案，其中A组同时联合腹部热疗；C组则采用紫杉醇+顺铂化疗方案。行为期3年随访，比对3组患者近、远期疗效及生存率，分析其不良反应发生情况，记录其生活质量评估差异。结果 A组近远期疗效及生活质量评估结果为3组最佳，其次为B组，C组最差（<0.05）；A、B组远期生存率及各Ⅱ-Ⅳ级不良反应发生率对比差异无统计学意义（>0.05），但均优于C组（<0.05）。结论对晚期胃癌患者予以介入化疗栓塞联合腹部热疗方案，近远期治疗效果均较为理想，不良反应较低，利于提高患者生存率及生存质量，值得临床推广。
目的：探討介入化療栓塞聯閤腹部熱療治療晚期胃癌的近遠期療效。方法選取該院收治的129例晚期胃癌患者為研究對象,根據其意願分成A、B、C3組，A、B組均予以介入化療栓塞方案，其中A組同時聯閤腹部熱療；C組則採用紫杉醇+順鉑化療方案。行為期3年隨訪，比對3組患者近、遠期療效及生存率，分析其不良反應髮生情況，記錄其生活質量評估差異。結果 A組近遠期療效及生活質量評估結果為3組最佳，其次為B組，C組最差（<0.05）；A、B組遠期生存率及各Ⅱ-Ⅳ級不良反應髮生率對比差異無統計學意義（>0.05），但均優于C組（<0.05）。結論對晚期胃癌患者予以介入化療栓塞聯閤腹部熱療方案，近遠期治療效果均較為理想，不良反應較低，利于提高患者生存率及生存質量，值得臨床推廣。
목적：탐토개입화료전새연합복부열료치료만기위암적근원기료효。방법선취해원수치적129례만기위암환자위연구대상,근거기의원분성A、B、C3조，A、B조균여이개입화료전새방안，기중A조동시연합복부열료；C조칙채용자삼순+순박화료방안。행위기3년수방，비대3조환자근、원기료효급생존솔，분석기불량반응발생정황，기록기생활질량평고차이。결과 A조근원기료효급생활질량평고결과위3조최가，기차위B조，C조최차（<0.05）；A、B조원기생존솔급각Ⅱ-Ⅳ급불량반응발생솔대비차이무통계학의의（>0.05），단균우우C조（<0.05）。결론대만기위암환자여이개입화료전새연합복부열료방안，근원기치료효과균교위이상，불량반응교저，리우제고환자생존솔급생존질량，치득림상추엄。
Objective To investigate the recent and long-term efficacy of interventional chemotherapy and embolization combined with abdominal thermotherapy in treatment of advanced gastric cancer.Methods 129 cases of advanced gastric cancer patients were selected as the subjects, according to its intention were divided into group A, group B, group C three groups, group A, group B were treated with interventional chemotherapy and embolization scheme, in which group A at the same time combined with abdominal thermotherapy; group C were treated with paclitaxel + cisplatin chemotherapy. Followed-up 3 year, compared behavior, near, long-term effect and survival rate in the three groups, analysis of toxic side reaction patients, recorded differences of evaluation of life quality.Results The short and long-term curative effect and quality of life assessment results in group A was the best of three groups, followed by group B, group C was the worst (<0.05); the difference of long-term survival rate and the II - IV toxicity compared incidence in group A, group B were no significant(>0.05), and were better than group C(<0.05).Conclusion Interventional chemoembolization combined with abdominal thermotherapy scheme on patients with advanced gastric cancer, the therapeutic effects is more ideal, toxicity is lower, can improve the survival rate and survival quality of patients, which is worthy of clinical promotion.
