CAJ | 학술논문

目的：以logistic回归分析结合roc曲线对2型糖尿病的危险因素进行分析。方法回顾该院2010年1月—2013年12月间收治的780例2型糖尿病肾病患者病历，并以800例健康人群作为对照组。以logistic回归分析对患者危险因素进行分析，以roc曲线患者检验学指标进行分析。结果年龄、糖尿病病程、肥胖、高血压病史、心脑血管疾病家族史是2型糖尿病的危险因素。roc曲线结果表明血清胱抑素C、糖化血红蛋白、尿微量白蛋白、同型半胱氨酸、C反应蛋白都可作为2型糖尿病肾病临床诊断指标， Youden指数达到1.837-1.953。结论临床可依据2型糖尿病患者临床资料以及检验学指标进行综合分析。
목적：이logistic회귀분석결합roc곡선대2형당뇨병적위험인소진행분석。방법회고해원2010년1월—2013년12월간수치적780례2형당뇨병신병환자병력，병이800례건강인군작위대조조。이logistic회귀분석대환자위험인소진행분석，이roc곡선환자검험학지표진행분석。결과년령、당뇨병병정、비반、고혈압병사、심뇌혈관질병가족사시2형당뇨병적위험인소。roc곡선결과표명혈청광억소C、당화혈홍단백、뇨미량백단백、동형반광안산、C반응단백도가작위2형당뇨병신병림상진단지표， Youden지수체도1.837-1.953。결론림상가의거2형당뇨병환자림상자료이급검험학지표진행종합분석。
Objective To analyze the risk factors of type 2 diabetes mellitus(T2DM) by the methods of logistic regression and ROC curve.Methods A retrospective analysis was conducted on the clinical data of 780 cases with type 2 diabetic nephropathy admitted in our hospital from January 2010 to December 2013. And other 800 healthy people were selected as the control group. The risk factors of the patients were analyzed by the method of logistic regression, and the test indexes were analyzed by ROC curve.Results Age, duration of diabetes, obesity, history of hypertension and family history of cardio-cerebrovascular disease would be the risk factors of type 2 diabetes. Serum cystatin C, glycosylated hemoglobin, urinary microalbumin, homocysteine and C-reactive protein would be regarded as the clinical diagnostic indexes of type 2 diabetic nephropathy, Youden’s index:1.837-1.953.Conclusion Comprehensive analysis of type 2 diabetes mellitus should be based on the clinical data of the patients and the test indexes.