CAJ | 학술논문

目的：比较全切术与次全切术治疗分化型甲状腺癌的疗效,评价两种手术的安全性。方法选取2010年12月—2013年12月收治的分化型甲状腺癌患者90例作为研究对象,分为全切组与次全切组,各45例,对比两组患者的疗效和并发症发生情况。结果全切组手术时间、术中出血量明显优于次全切组(＜0.05)；住院时间组间比较差异不明显(＞0.05)；全切组患者的复发率为0,明显低于次全切组的13.33%(＜0.05)；全切组的并发症发生率为28.89%,明显高于次全切组的4.44%(＜0.05)。结论分化型甲状腺癌全切术手术时间短,术中出血量少,但低钙血症和甲状旁腺功能减退的发生率较高,临床医生需要根据患者的具体情况选择手术方式。
목적：비교전절술여차전절술치료분화형갑상선암적료효,평개량충수술적안전성。방법선취2010년12월—2013년12월수치적분화형갑상선암환자90례작위연구대상,분위전절조여차전절조,각45례,대비량조환자적료효화병발증발생정황。결과전절조수술시간、술중출혈량명현우우차전절조(＜0.05)；주원시간조간비교차이불명현(＞0.05)；전절조환자적복발솔위0,명현저우차전절조적13.33%(＜0.05)；전절조적병발증발생솔위28.89%,명현고우차전절조적4.44%(＜0.05)。결론분화형갑상선암전절술수술시간단,술중출혈량소,단저개혈증화갑상방선공능감퇴적발생솔교고,림상의생수요근거환자적구체정황선택수술방식。
Objective To compare the curative effect between total resection and subtotal resection in the treatment of differentiated thyroid cancer and evaluate the safety of these two kinds of operation.Methods 90 cases with differentiated thyroid cancer admitted from December 2010 to December 2013 were selected as the subjects and divided into the total resection group and subtotal resection group, 45 cases in each group. And the curative effect and incidence of complications were compared between the two groups.Results Compared with the subtotal resection group, the duration of operation and intraoperative blood loss of the total resection group were much less(<0.05); the difference in the length of stay between the two groups was not significant(>0.05); the recurrence rate of the total resection group was 0, much lower than 13.33% of the subtotal resection group(<0.05); the incidence of complications of the total resection group was 28.89%, much higher than 4.44% of the subtotal resection group(<0.05).Conclusion For the treatment of differentiated thyroid cancer, the total resection has shorter duration of operation, less intraoperative blood loss but higher incidence of hypocalcemia and hypoparathyroidism, so the operation mode should be selected in accordance with the specific conditions of the patients.