中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
14期
60-62
,共3页
三维适形放疗%简化调强放疗%适形调强放疗%直肠癌术后
三維適形放療%簡化調彊放療%適形調彊放療%直腸癌術後
삼유괄형방료%간화조강방료%괄형조강방료%직장암술후
Three dimensional conformal radiotherapy%Simplified intensity-modulated technique%Intensity-modulated conformal radiotherapy%After rectal carcinoma
目的：比较三维适形放疗、简化调强放疗和适形调强放疗在直肠癌术后放疗中的三维剂量学差异。方法选择2008年1月~2013年1月在本院进行直肠癌术后放疗且无放疗禁忌证患者342例,分别使用三维适形放疗、简化调强放疗以及适形调强放疗方案,按照国际标准评价方法比较3种放疗方案的靶区平均剂量、靶区适形指数、剂量不均性指数及子野机器跳数。结果靶区平均剂量院三维适形放疗比简化调强放疗、适形调强放疗剂量要高,差异有统计学意义(P<0.05),简化调强放疗与适形调强放疗差异无统计学意义(P跃0.05)。靶区适形指数院三维适形放疗指数最低(P<0.05),简化调强放疗与适形调强放疗差异无统计学意义(P跃0.05)。剂量不均性指数院适形调强放疗最高,简化调强放疗最低,3种方案差异有统计学意义(P<0.05)。适形调强放疗的子野机器跳数明显高于三维适形放疗、简化调强放疗,差异有统计学意义(P<0.05),三维适形放疗与简化调强放疗差异无统计学意义(P跃0.05)。结论3种化疗方案中,简化调强技术性价比最好,值得临床推广应用。
目的：比較三維適形放療、簡化調彊放療和適形調彊放療在直腸癌術後放療中的三維劑量學差異。方法選擇2008年1月~2013年1月在本院進行直腸癌術後放療且無放療禁忌證患者342例,分彆使用三維適形放療、簡化調彊放療以及適形調彊放療方案,按照國際標準評價方法比較3種放療方案的靶區平均劑量、靶區適形指數、劑量不均性指數及子野機器跳數。結果靶區平均劑量院三維適形放療比簡化調彊放療、適形調彊放療劑量要高,差異有統計學意義(P<0.05),簡化調彊放療與適形調彊放療差異無統計學意義(P躍0.05)。靶區適形指數院三維適形放療指數最低(P<0.05),簡化調彊放療與適形調彊放療差異無統計學意義(P躍0.05)。劑量不均性指數院適形調彊放療最高,簡化調彊放療最低,3種方案差異有統計學意義(P<0.05)。適形調彊放療的子野機器跳數明顯高于三維適形放療、簡化調彊放療,差異有統計學意義(P<0.05),三維適形放療與簡化調彊放療差異無統計學意義(P躍0.05)。結論3種化療方案中,簡化調彊技術性價比最好,值得臨床推廣應用。
목적：비교삼유괄형방료、간화조강방료화괄형조강방료재직장암술후방료중적삼유제량학차이。방법선택2008년1월~2013년1월재본원진행직장암술후방료차무방료금기증환자342례,분별사용삼유괄형방료、간화조강방료이급괄형조강방료방안,안조국제표준평개방법비교3충방료방안적파구평균제량、파구괄형지수、제량불균성지수급자야궤기도수。결과파구평균제량원삼유괄형방료비간화조강방료、괄형조강방료제량요고,차이유통계학의의(P<0.05),간화조강방료여괄형조강방료차이무통계학의의(P약0.05)。파구괄형지수원삼유괄형방료지수최저(P<0.05),간화조강방료여괄형조강방료차이무통계학의의(P약0.05)。제량불균성지수원괄형조강방료최고,간화조강방료최저,3충방안차이유통계학의의(P<0.05)。괄형조강방료적자야궤기도수명현고우삼유괄형방료、간화조강방료,차이유통계학의의(P<0.05),삼유괄형방료여간화조강방료차이무통계학의의(P약0.05)。결론3충화료방안중,간화조강기술성개비최호,치득림상추엄응용。
Objective To compare the difference of three dimensional dosimetry for hree dimensional conformal radio-therapy, simplified intensity-modulated technique and intensity-modulated conformal radiotherapy in postoperative ra-diotherapy of rectal carcinoma. Methods 342 patients without contraindication of radiotherapy who received radiothera-py after rectal carcinoma operation in our hospital from January 2008 to January 2013 were selected.They were given three different schemes of three dimensional conformal radiotherapy,simplified intensity-modulated radiotherapy and intensity-modulated conformal radiotherapy respectively.Mean dosage in target region,conformal index in target region, and dose heterogeneity index and machine unit (MU) of segment of three kinds of radiotherapy plan was compared re-spectively. Results As for mean dosage in target region, dosage of three-dimensional conformal radiotherapy was higher than that of simplified intensity-modulated radiotherapy and intensity-modulated conformal radiotherapy,and there was a statistical difference (P<0.05).There was no statistical difference between simplified intensity-modulated radiotherapy and intensity-modulated conformal radiotherapy (P>0.05).As for conformal index in target region,index of three dimen-sional conformal radiotherapy was the lowest, and the difference was statistically significant (P<0.05).There was no sta-tistical difference between simplified intensity-modulated radiotherapy and intensity-modulated conformal radiotherapy (P>0.05).As for dose heterogeneity index,index of intensity-modulated conformal radiotherapy was the highest,and the index of simplified intensity-modulated radiotherapy was the lowest and there was a statistical difference among three kinds of method (P<0.05).As for MU of segment,intensity-modulated conformal radiotherapy was significantly higher than that of three dimensional conformal radiotherapy and simplified intensity-modulated radiotherapy,and the differ-ences between groups were statistically significant (P<0.05).There was no statistical difference between three dimen-sional conformal radiotherapy and simplified intensity-modulated radiotherapy (P>0.05). Conclusion Among three schemes of radiotherapy,cost performance of simplified intensity-modulated technique is the best,and it is worthy of clinical promotion and application.
