中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
14期
57-59,62
,共4页
光动力治疗%支架置入%食管肿瘤%气道阻塞
光動力治療%支架置入%食管腫瘤%氣道阻塞
광동력치료%지가치입%식관종류%기도조새
Photodynamic therapy%Stent implantation%Esophageal neoplasm%Airway obstruction
目的：比较单纯支架置入与光动力治疗联合支架置入治疗食管癌所致气道狭窄的效果。方法2009年10月~2014年10月,收集武安市第一人民医院胸外科食管癌引起中央气道狭窄患者25例,将其随机分为两组,12例(试验组)给予支架置入后行光动力治疗,13例(对照组)行单纯支架置入,比较两组患者的气促评分情况、平均稳定期、平均生存期及并发症发生率。结果两组的气促评分改善情况差异无统计学意义(P跃0.05)；试验组患者的平均稳定期、平均生存期明显延长(P<0.05),支气管再狭窄发生率降低(P<0.05)。结论光动力治疗联合支架置入是治疗食管癌所致气道狭窄的一项有效姑息治疗方法,可延长平均稳定期和平均生存期,降低支气管再狭窄发生率。
目的：比較單純支架置入與光動力治療聯閤支架置入治療食管癌所緻氣道狹窄的效果。方法2009年10月~2014年10月,收集武安市第一人民醫院胸外科食管癌引起中央氣道狹窄患者25例,將其隨機分為兩組,12例(試驗組)給予支架置入後行光動力治療,13例(對照組)行單純支架置入,比較兩組患者的氣促評分情況、平均穩定期、平均生存期及併髮癥髮生率。結果兩組的氣促評分改善情況差異無統計學意義(P躍0.05)；試驗組患者的平均穩定期、平均生存期明顯延長(P<0.05),支氣管再狹窄髮生率降低(P<0.05)。結論光動力治療聯閤支架置入是治療食管癌所緻氣道狹窄的一項有效姑息治療方法,可延長平均穩定期和平均生存期,降低支氣管再狹窄髮生率。
목적：비교단순지가치입여광동력치료연합지가치입치료식관암소치기도협착적효과。방법2009년10월~2014년10월,수집무안시제일인민의원흉외과식관암인기중앙기도협착환자25례,장기수궤분위량조,12례(시험조)급여지가치입후행광동력치료,13례(대조조)행단순지가치입,비교량조환자적기촉평분정황、평균은정기、평균생존기급병발증발생솔。결과량조적기촉평분개선정황차이무통계학의의(P약0.05)；시험조환자적평균은정기、평균생존기명현연장(P<0.05),지기관재협착발생솔강저(P<0.05)。결론광동력치료연합지가치입시치료식관암소치기도협착적일항유효고식치료방법,가연장평균은정기화평균생존기,강저지기관재협착발생솔。
Objective To compare the effect of simple stent implantation and photodynamic therapy (PDT) combined with stent implantation in the treatment of airway stenosis caused by esophageal cancer. Methods From October 2009 to October 2014,25 patients with central airway stenosis caused by esophageal cancer treated in department of thoracic surgery of the First People’s Hospital of Wuan City were selected and they were randomly divided into two groups.12 patients (experimental group) were given PDT after stent implantation,while the other 13 patients (control group) was given simple stent implantation.Shortbreath score,mean stable time,mean survival time and incidence rate of complica-tion between two groups was compared respectively. Results There was no statistical difference of shortbreath score be-tween two groups (P>0.05).Mean stable time and mean survival time was significantly proloned in patients of experi-mental group and incidence rate of bronchial stenosis again was obviously decreased (P<0.05). Conclusion Photody-namic therapy combined with stent implantation is an effective palliative treatment method of treating airway stenosis caused by esophageal cancer and it can prolong the stable time and mean survival time,and reduce the incidence rate of bronchial stenosis again.
