中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
14期
43-45
,共3页
系统性红斑狼疮%消化系统%诊断
繫統性紅斑狼瘡%消化繫統%診斷
계통성홍반랑창%소화계통%진단
Systemic lupus erythematosus(SLE)%Digestive System%Diagnosis
目的：探讨系统性红斑狼疮(SLE)消化道受累的临床特征和实验室检查结果,为早期诊断、早期治疗及改善预后提供临床依据。方法回顾性分析2006年12月~2013年12月本院收治的30例消化系统受累的SLE患者的临床资料和实验室检查结果,选择同期60例无消化系统受累的SLE患者作为对照组,比较实验结果。结果 SLE消化系统受累的患者,消化系统各个部位皆可受累,SLE消化系统受累更容易合并泌尿系统受累,血清白蛋白、C3水平、CH50水平、ANCA阳性率、D二聚体水平等与对照组比较,差异有统计学意义(P<0.05)。结论 SLE消化系统受累较为常见,部分为SLE患者的首发表现。 SLE消化系统受累多属狼疮重症,预后不良,需要较大剂量的激素及免疫抑制剂治疗,抗凝治疗较为重要,临床应予以重视,早期诊断、早期治疗,改善预后。在临床实践中有指导意义。
目的：探討繫統性紅斑狼瘡(SLE)消化道受纍的臨床特徵和實驗室檢查結果,為早期診斷、早期治療及改善預後提供臨床依據。方法迴顧性分析2006年12月~2013年12月本院收治的30例消化繫統受纍的SLE患者的臨床資料和實驗室檢查結果,選擇同期60例無消化繫統受纍的SLE患者作為對照組,比較實驗結果。結果 SLE消化繫統受纍的患者,消化繫統各箇部位皆可受纍,SLE消化繫統受纍更容易閤併泌尿繫統受纍,血清白蛋白、C3水平、CH50水平、ANCA暘性率、D二聚體水平等與對照組比較,差異有統計學意義(P<0.05)。結論 SLE消化繫統受纍較為常見,部分為SLE患者的首髮錶現。 SLE消化繫統受纍多屬狼瘡重癥,預後不良,需要較大劑量的激素及免疫抑製劑治療,抗凝治療較為重要,臨床應予以重視,早期診斷、早期治療,改善預後。在臨床實踐中有指導意義。
목적：탐토계통성홍반랑창(SLE)소화도수루적림상특정화실험실검사결과,위조기진단、조기치료급개선예후제공림상의거。방법회고성분석2006년12월~2013년12월본원수치적30례소화계통수루적SLE환자적림상자료화실험실검사결과,선택동기60례무소화계통수루적SLE환자작위대조조,비교실험결과。결과 SLE소화계통수루적환자,소화계통각개부위개가수루,SLE소화계통수루경용역합병비뇨계통수루,혈청백단백、C3수평、CH50수평、ANCA양성솔、D이취체수평등여대조조비교,차이유통계학의의(P<0.05)。결론 SLE소화계통수루교위상견,부분위SLE환자적수발표현。 SLE소화계통수루다속랑창중증,예후불량,수요교대제량적격소급면역억제제치료,항응치료교위중요,림상응여이중시,조기진단、조기치료,개선예후。재림상실천중유지도의의。
Objective To study the clinical features and laboratory examination results of systemic lupus erythematosus (SLE) with digestive system involvement,and provide clinical evidence for early diagnosis,early treatment and the prog-nosis. Methods 30 patients with digestive system involvement SLE in our hospital from December 2006 to December 2013 were selected and clinical data and laboratory test results was analysied retrospectively.60 patients without gas-trointestinal involvement in SLE patients as control group at the same time,the experimental results was compared be-tween two groups. Results SLE digestive system involvement in patients with digestive system,each part was affected, SLE gastrointestinal involvement was more easily combined with urinary system involvement,serum albumin level,C3, CH50 level,positive rate of ANCA,D-dimer level was compared respectively with control group,with statistical difference (P<0.05). Conclusion SLE with digestive system is common,and part is the first manifestation of SLE patients.Digestive system involvement in SLE is severe lupus,poor prognosis and need larger doses of hormones and immunosuppressive therapy,anticoagulant therapy is more important,clinical should pay more attention to it,early diagnosis,early treatment and improve the prognosis.Have the guiding significance in clinical practice.
