中国医药导报
中國醫藥導報
중국의약도보
CHINA MEDICAL HERALD
2015年
15期
154-156,162
,共4页
李婛%季兴%邹东华%王荔
李婛%季興%鄒東華%王荔
리경%계흥%추동화%왕려
运动疗法%脑梗死%脑源性神经营养因子
運動療法%腦梗死%腦源性神經營養因子
운동요법%뇌경사%뇌원성신경영양인자
Exercise therapy%Cerebral infarction%Brain-derived neurotrophic factor
目的：探讨运动疗法对急性脑梗死患者血中的脑源性神经营养因子(BDNF)的影响。方法选取2013年9月~2014年9月解放军第三〇三医院收治的急性脑梗死患者30例，以同意运动治疗的18例为运动组，以不同意运动治疗的12例为对照组。运动组给予良肢体位摆放和被动运动，并同时给予抗血小板聚集、改善循环、营养神经、扩张脑血管等治疗。对照组只给予抗血小板聚集、改善循环、营养神经、扩张脑血管等治疗。采用酶联免疫吸附法(ELISA)检测治疗前，治疗后1、2周血液中的BDNF水平。结果两组治疗后BDNF水平均高于治疗前，差异有统计学意义(P<0.05)；运动组治疗后14 d BDNF水平[(101.03±3.34)pg/mg]高于治疗后7 d[(68.12±1.41)pg/mg]，差异有统计学意义(P<0.05)；运动组治疗后7、14 d BDNF水平均高于对照组[(66.17±1.32)、(77.15±2.29)pg/mg]，差异有统计学意义(P<0.05)。对照组有效率(75.0%)明显低于运动组(88.9%)，差异有高度统计学意义(P<0.01)。结论运动疗法可以促进DBNF的表达以及改善患者临床症状。
目的：探討運動療法對急性腦梗死患者血中的腦源性神經營養因子(BDNF)的影響。方法選取2013年9月~2014年9月解放軍第三〇三醫院收治的急性腦梗死患者30例，以同意運動治療的18例為運動組，以不同意運動治療的12例為對照組。運動組給予良肢體位襬放和被動運動，併同時給予抗血小闆聚集、改善循環、營養神經、擴張腦血管等治療。對照組隻給予抗血小闆聚集、改善循環、營養神經、擴張腦血管等治療。採用酶聯免疫吸附法(ELISA)檢測治療前，治療後1、2週血液中的BDNF水平。結果兩組治療後BDNF水平均高于治療前，差異有統計學意義(P<0.05)；運動組治療後14 d BDNF水平[(101.03±3.34)pg/mg]高于治療後7 d[(68.12±1.41)pg/mg]，差異有統計學意義(P<0.05)；運動組治療後7、14 d BDNF水平均高于對照組[(66.17±1.32)、(77.15±2.29)pg/mg]，差異有統計學意義(P<0.05)。對照組有效率(75.0%)明顯低于運動組(88.9%)，差異有高度統計學意義(P<0.01)。結論運動療法可以促進DBNF的錶達以及改善患者臨床癥狀。
목적：탐토운동요법대급성뇌경사환자혈중적뇌원성신경영양인자(BDNF)적영향。방법선취2013년9월~2014년9월해방군제삼〇삼의원수치적급성뇌경사환자30례，이동의운동치료적18례위운동조，이불동의운동치료적12례위대조조。운동조급여량지체위파방화피동운동，병동시급여항혈소판취집、개선순배、영양신경、확장뇌혈관등치료。대조조지급여항혈소판취집、개선순배、영양신경、확장뇌혈관등치료。채용매련면역흡부법(ELISA)검측치료전，치료후1、2주혈액중적BDNF수평。결과량조치료후BDNF수평균고우치료전，차이유통계학의의(P<0.05)；운동조치료후14 d BDNF수평[(101.03±3.34)pg/mg]고우치료후7 d[(68.12±1.41)pg/mg]，차이유통계학의의(P<0.05)；운동조치료후7、14 d BDNF수평균고우대조조[(66.17±1.32)、(77.15±2.29)pg/mg]，차이유통계학의의(P<0.05)。대조조유효솔(75.0%)명현저우운동조(88.9%)，차이유고도통계학의의(P<0.01)。결론운동요법가이촉진DBNF적표체이급개선환자림상증상。
Objective Exercise therapy on acute cerebral infarction patients blood the effects of BDNF. Methods From September 2013 to September 2014, in the 303rd Hospital of PLA, 30 patients with acute cerebral infarction were se-lected, 18 patients agreed with exercise therapy were as exercise group, 12 disagreed with exercise therapy were as control group. The exercise group were given good body position and passive movement, at the same time the platelet aggregation, improve circulation, nerve nutrition, expansion and cerebrovascular treatment were given. The control group were given the platelet aggregation, improve circulation, nerve nutrition, expansion and cerebrovascular treatment. Be-fore the treatment and after the treatment 1, 2 weeks, the BDNF of blood was detected by ELISA. Results After the treatmnet, BDNF in two groups were higher than those before the treatment, the differences were statistically significant (P< 0.05); BDNF in exercise group after the treatment 14 days [(101.03±3.34)pg/mg] was higher than that after the treatment 7 days [(68.12±1.41)pg/mg], the difference was statistically significant (P< 0.05); BDNF in after the treat-ment 7, 14 days were higher than those in control group [(66.17±1.32), (77.15±2.29)pg/mg], the differences were statis-tically significant (P<0.05). The effective rate of control group (75.0%) was lower than that of exercise group (88.9%), the difference was statistically significant (P<0.01). Conclusion Exercise therapy can promote the expression of DBNF and improve patients' clinical symptoms.
