CAJ | 학술논문

目的：探讨依达拉奉联合奥拉西坦治疗大面积脑梗死的临床效果。方法随机将136例大面积脑梗死患者分为观察组和对照组，每组68例。观察组采用依达拉奉联合奥拉西坦进行治疗。对照组单纯给予奥拉西坦进行治疗。比较两组临床有效率、NIHSS评分、CSS评分。结果观察组患者总有效率为95.59%，对照组患者总有效率为79.41%。观察组总有效率优于对照组，P＜0.05，差异具有统计学意义。治疗半个月后，两组NIHSS、CSS评分均优于治疗前，但观察组改善幅度优于对照组，P＜0.05，差异具有统计学意义。结论依达拉奉与奥拉西坦联合治疗大面积脑梗死临床效果显著，同时可改善患者神经功能，提高患者生活质量，安全性高。
목적：탐토의체랍봉연합오랍서탄치료대면적뇌경사적림상효과。방법수궤장136례대면적뇌경사환자분위관찰조화대조조，매조68례。관찰조채용의체랍봉연합오랍서탄진행치료。대조조단순급여오랍서탄진행치료。비교량조림상유효솔、NIHSS평분、CSS평분。결과관찰조환자총유효솔위95.59%，대조조환자총유효솔위79.41%。관찰조총유효솔우우대조조，P＜0.05，차이구유통계학의의。치료반개월후，량조NIHSS、CSS평분균우우치료전，단관찰조개선폭도우우대조조，P＜0.05，차이구유통계학의의。결론의체랍봉여오랍서탄연합치료대면적뇌경사림상효과현저，동시가개선환자신경공능，제고환자생활질량，안전성고。
Objective To explore the curative effect on edaravone combined with olathe of treatment extensive cerebral infarction. Methods 136 cases with extensive cerebral infarction were randomly divided into the observation group and the control group, each group has 68 cases. Observation group adopt edaravone oxiracetam treatment. The control group were given oxiracetam treatment. Comparied two clinical efifciency, NIHSS score, CSS score. Results Observation group of patients total effective rate was 95.59%, the control group of patients the total effective rate was 79.41%. the observation group total effective rate was better than the control group, P<0.05, had difference statistically signiifcance. Half a month after treatment, two groups of NIHSS, CSS score were better than the before treatment, but the observation group improved range was better than the control group, P<0.05, had difference statistically significance. Conclusion The clinical effects on edaravone combine with oxiracetam to treatment massive cerebral infarction is remarkale, it can improve neurological function and i quality of life.