北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2015年
6期
98-98,99
,共2页
丹莪妇康煎膏%子宫内膜异位症%IL-17%IL-23
丹莪婦康煎膏%子宮內膜異位癥%IL-17%IL-23
단아부강전고%자궁내막이위증%IL-17%IL-23
Danefukang jiangao%Endometriosis%IL-17%IL-23
目的：探讨丹莪妇康煎膏对子宫内膜异位症（EMS）模型大鼠血清中炎性因子IL-17和IL-23表达的影响。方法：自体子宫内膜移植法建立EMS大鼠模型，SD大鼠随机分为空白组、模型组和治疗组，以ELISA法监测各组大鼠血清中炎性因子IL-17和IL-23表达的变化。结果：与模型组相比，治疗组大鼠血清中IL-17和IL-23表达水平明显下调，差异有统计学意义（P<0.05）。结论：丹莪妇康煎膏治疗子宫内膜异位症的机制之一可能与抑制炎性因子的表达有关。
目的：探討丹莪婦康煎膏對子宮內膜異位癥（EMS）模型大鼠血清中炎性因子IL-17和IL-23錶達的影響。方法：自體子宮內膜移植法建立EMS大鼠模型，SD大鼠隨機分為空白組、模型組和治療組，以ELISA法鑑測各組大鼠血清中炎性因子IL-17和IL-23錶達的變化。結果：與模型組相比，治療組大鼠血清中IL-17和IL-23錶達水平明顯下調，差異有統計學意義（P<0.05）。結論：丹莪婦康煎膏治療子宮內膜異位癥的機製之一可能與抑製炎性因子的錶達有關。
목적：탐토단아부강전고대자궁내막이위증（EMS）모형대서혈청중염성인자IL-17화IL-23표체적영향。방법：자체자궁내막이식법건립EMS대서모형，SD대서수궤분위공백조、모형조화치료조，이ELISA법감측각조대서혈청중염성인자IL-17화IL-23표체적변화。결과：여모형조상비，치료조대서혈청중IL-17화IL-23표체수평명현하조，차이유통계학의의（P<0.05）。결론：단아부강전고치료자궁내막이위증적궤제지일가능여억제염성인자적표체유관。
Objective:To investigate the effect of Danefukang jiangao on the expression of inflammatory factor of endometriotic rats. Methods:Rats were randomly divided into 3 groups:control group,model group and Danefukang jiangao treatment group. The expression of IL-17 and IL-23 were detected by ELISA. Results:Compared with the model group,the expression of IL-17 and IL-23 were decreased significantly in Danefukang jiangao treatment group. Conclusion:The Danefukang jiangao can treat the endometriosis in rats, and its action may be associated with decreasing the expressions of IL-17 and IL-23 in ectopic endometrium.
