北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2015年
6期
124-124,125
,共2页
乌司他丁%奥曲肽%重症急性胰腺炎%联合应用
烏司他丁%奧麯肽%重癥急性胰腺炎%聯閤應用
오사타정%오곡태%중증급성이선염%연합응용
Ulinastatin%Mr Qu peptide%Severe acute pancreatitis%The joint application
目的：探讨乌司他丁联合奥曲肽在治疗重症急性胰腺炎中的临床效果。方法：选取2012年7月～2014年6月于我院就诊的重症急性胰腺炎患者86例作为研究对象，随机分为两组，对照组与观察组各43例，对照组在常规治疗基础上单用奥曲肽治疗，观察组在常规治疗基础上采用乌司他丁联合奥曲肽治疗，对比两组治疗效果以及各指标的变化情况。结果：观察组治疗总有效率为88.37%，对照组治疗总有效率为69.77%，对比两组治疗效果，观察组明显优于对照组，差异显著（X2=4.497，P=0.034）；观察组患者的血淀粉酶恢复时间、尿淀粉酶恢复时间、腹痛改善时间以及平均住院天数均显著短于对照组，具有明显差异（P<0.05）。结论：重症急性胰腺炎采用乌司他丁联合奥曲肽治疗相比于单用奥曲肽治疗，疗效更为显著，可以明显改善临床症状，促进患者康复，存在较高的临床应用价值。
目的：探討烏司他丁聯閤奧麯肽在治療重癥急性胰腺炎中的臨床效果。方法：選取2012年7月～2014年6月于我院就診的重癥急性胰腺炎患者86例作為研究對象，隨機分為兩組，對照組與觀察組各43例，對照組在常規治療基礎上單用奧麯肽治療，觀察組在常規治療基礎上採用烏司他丁聯閤奧麯肽治療，對比兩組治療效果以及各指標的變化情況。結果：觀察組治療總有效率為88.37%，對照組治療總有效率為69.77%，對比兩組治療效果，觀察組明顯優于對照組，差異顯著（X2=4.497，P=0.034）；觀察組患者的血澱粉酶恢複時間、尿澱粉酶恢複時間、腹痛改善時間以及平均住院天數均顯著短于對照組，具有明顯差異（P<0.05）。結論：重癥急性胰腺炎採用烏司他丁聯閤奧麯肽治療相比于單用奧麯肽治療，療效更為顯著，可以明顯改善臨床癥狀，促進患者康複，存在較高的臨床應用價值。
목적：탐토오사타정연합오곡태재치료중증급성이선염중적림상효과。방법：선취2012년7월～2014년6월우아원취진적중증급성이선염환자86례작위연구대상，수궤분위량조，대조조여관찰조각43례，대조조재상규치료기출상단용오곡태치료，관찰조재상규치료기출상채용오사타정연합오곡태치료，대비량조치료효과이급각지표적변화정황。결과：관찰조치료총유효솔위88.37%，대조조치료총유효솔위69.77%，대비량조치료효과，관찰조명현우우대조조，차이현저（X2=4.497，P=0.034）；관찰조환자적혈정분매회복시간、뇨정분매회복시간、복통개선시간이급평균주원천수균현저단우대조조，구유명현차이（P<0.05）。결론：중증급성이선염채용오사타정연합오곡태치료상비우단용오곡태치료，료효경위현저，가이명현개선림상증상，촉진환자강복，존재교고적림상응용개치。
Objective:To explore discuss the Ulinastatin combine the application effect the safety Of octreotide in severe acute pancreatitis. Methods:Selected in July 2013 to June 2014 in our hospital 86 cases of severe acute pancreatitis patients as the research object, the patients were randomly divided into two groups, control group and observation group, 43 patients in the control group on the basis of routine therapy in patients with Mr Octreotide therapy, observation group of patients on the basis of conventional treatment using ulinastatin combined therapy with Mr Qu peptide, contrast the curative effect of two groups of patients, and the change of various index. Results:The treatment group total effectiveness 88.37%, control group total effective rate was 69.77%, compared the therapeutic effect of two groups of patients, observation group was better than control group, there is significant difference (X2=4.497,P=0.034);Observation group of patients with blood amylase recovery time, urine amylase recovery time, abdominal pain, improve time and average hospitalization days were significantly shorter than the control group, with significant difference (P<0.05). Conclusion: Severe acute pancreatitis using ulinastatin combined the octreotide therapy compared to use the peptide treatment, the curative effect is more significant, can significantly improve the clinical symptoms, promote patients recovery, has high clinical value, can be promoted application in clinic.
