CAJ | 학술논문

目的：观察曲美他嗪治疗酒精性心肌病的临床效果。方法选取该院在2013年10月-2014年10月收治的26例酒精性心肌病患者为观察组，在常规治疗基础上联合曲美他嗪；选取该院在2012年9月-2013年9月收治的30例酒精性心肌病患者为对照组，单纯采用常规治疗，对比两组患者的治疗效果。结果①观察组患者的临床治疗总有效率(92.31豫)明显高于对照组(70.00豫)(P<0.05)；②经治疗后，两组患者的6 min步行距离、LVEF、CRP均较治疗前显著改善(P<0.05)，但观察组患者的改善程度显著优于对照组(P<0.05)。结论对于酒精性心肌病患者，在常规治疗的基础上加用曲美他嗪，可以有效提升治疗效果，且能显著改善患者的6 min步行距离、LVEF、CRP，效果显著，值得临床推广。
목적：관찰곡미타진치료주정성심기병적림상효과。방법선취해원재2013년10월-2014년10월수치적26례주정성심기병환자위관찰조，재상규치료기출상연합곡미타진；선취해원재2012년9월-2013년9월수치적30례주정성심기병환자위대조조，단순채용상규치료，대비량조환자적치료효과。결과①관찰조환자적림상치료총유효솔(92.31예)명현고우대조조(70.00예)(P<0.05)；②경치료후，량조환자적6 min보행거리、LVEF、CRP균교치료전현저개선(P<0.05)，단관찰조환자적개선정도현저우우대조조(P<0.05)。결론대우주정성심기병환자，재상규치료적기출상가용곡미타진，가이유효제승치료효과，차능현저개선환자적6 min보행거리、LVEF、CRP，효과현저，치득림상추엄。
Objective To observe the clinical effect of trimetazidine in the treatment of alcoholic cardiomyopathy. Methods Select our hospital in October 2013 to October 2014, 26 patients with alcoholic cardiomyopathy as the observation group, on the basis of conventional treatment combined trimetazidine. Select our hospital in September 2012 to September 2013 were as control group, 30 patients with alcoholic cardiomyopathy only with conventional treatment, compared the therapeutic effect of two groups of pa-tients. Results①The clinical total effective rate of observation group of patients (92.31%) is significantly higher than control group (70.00%) (P<0.05);②after treatment, two groups of patients with 6 min walking distance, LVEF, CRP was significantly improve the (P< 0.05), but the observation group of patients significantly improve is better than that of control group (P< 0.05). Conclu-sion For patients with alcoholic cardiomyopathy, on the basis of conventional treatment combined with trimetazidine, can enhance the treatment effect, and can significantly improve the patient's 6 min walking distance, LVEF, CRP, obvious effect, worth clinical promotion.