CAJ | 학술논문

目的：观察铝碳酸镁联合多潘立酮治疗胆汁反流性胃炎的临床疗效。方法：142例胆汁反流性胃炎患者，随机分为两组各71例，对照组给予多潘立酮治疗，观察组在对照组的基础上加用铝碳酸镁联合治疗，比较两组临床疗效。结果：观察组与对照组的有效率分别为95.77％、76.06％，差异显著（X2=11.41，P<0.01）。疗程结束后，观察组临床症状上腹痛、恶心、腹胀积分优于对照组，差异有统计学意义（P<0.01）。观察组24h胆汁监测最长反流时间、反流总时间、反流大于5min次数均优于对照组，差异显著（P<0.05）。结论：铝碳酸镁联合多潘立酮治疗胆汁反流性胃炎，两者联用具有协同作用，比单用多潘立酮的治疗效果显著，值得临床推广。
목적：관찰려탄산미연합다반립동치료담즙반류성위염적림상료효。방법：142례담즙반류성위염환자，수궤분위량조각71례，대조조급여다반립동치료，관찰조재대조조적기출상가용려탄산미연합치료，비교량조림상료효。결과：관찰조여대조조적유효솔분별위95.77％、76.06％，차이현저（X2=11.41，P<0.01）。료정결속후，관찰조림상증상상복통、악심、복창적분우우대조조，차이유통계학의의（P<0.01）。관찰조24h담즙감측최장반류시간、반류총시간、반류대우5min차수균우우대조조，차이현저（P<0.05）。결론：려탄산미연합다반립동치료담즙반류성위염，량자련용구유협동작용，비단용다반립동적치료효과현저，치득림상추엄。
Objective To investigate the joint domperidone hydrotalcid clinical efficacy of bile reflux gastritis treatment. Methods 142 cases of bile reflux gastritis patients were randomly divided into two groups, each of 71 cases in the control group were treated with domperidone treatment, observation group aluminum magnesium combination therapy on the basis of the control group, the clinical efficacy of two groups were compared. Results of the observation group and the control group response rate was 95.77%, respectively, 76.06%, compare the two groups was significant difference (X2 = 11.41, P<0.01). After treatment, the clinical course of abdominal symptoms in patients treated, nausea, bloating integration than the control group, the difference was statistically significant (P<0.01). Treated 24 h bile reflux monitoring the longest time, the total time of reflux, regurgitation greater than 5min times than the control group difference was significant statistically significant. Conclusion hydrotalcid joint domperidone treatment bile reflux gastritis, both combined with a synergistic effect, than the single use of domperidone treatment effect is more significant, worthy of clinical application.