CAJ | 학술논문

目的：对依托咪酯与咪达唑仑辅助麻醉临床比较，从而挑选出最适合最为辅助麻醉的药物。方法选取我院2010年1月～2014年6月184例区域麻醉患者，按照自愿原则分为依托咪酯组和咪达唑仑组，依托咪酯组应用依托咪酯进行辅助麻醉，咪达唑仑组应用咪达唑仑进行辅助麻醉．分析对比两组患者药物应用前后血流动力学改变情况，P＜0.05，差异具有统计学意义。结果依托咪酯组药物应用前后平均动脉压、心率、氧饱和度对比，P＞0.05，差异不具有统计学意义，咪达唑仑组平均动脉压、心率、氧饱和度在应用前后，P＜0.05，差异具有统计学意义。结论依托咪酯辅助麻醉具有较高安全性，不会导致呼吸与循环出现较高抑制性．所以患者在手术之后能够及时的苏醒，其安全性更高，特别是将其应用在休克患者中，其优势能够突显出来。
목적：대의탁미지여미체서륜보조마취림상비교，종이도선출최괄합최위보조마취적약물。방법선취아원2010년1월～2014년6월184례구역마취환자，안조자원원칙분위의탁미지조화미체서륜조，의탁미지조응용의탁미지진행보조마취，미체서륜조응용미체서륜진행보조마취．분석대비량조환자약물응용전후혈류동역학개변정황，P＜0.05，차이구유통계학의의。결과의탁미지조약물응용전후평균동맥압、심솔、양포화도대비，P＞0.05，차이불구유통계학의의，미체서륜조평균동맥압、심솔、양포화도재응용전후，P＜0.05，차이구유통계학의의。결론의탁미지보조마취구유교고안전성，불회도치호흡여순배출현교고억제성．소이환자재수술지후능구급시적소성，기안전성경고，특별시장기응용재휴극환자중，기우세능구돌현출래。
Objective Clinical comparison wiht etomidate and midazolam as midazolam assisted to pick out the most suitable for the assisted anesthesia drugs. Methods Selected 184 cases with regional anesthesia from January 2010 to June 2014 in our hospital, divided into etomidate group and midazolam group with the principle of voluntary, etomidate group applied etomidate were assisted anesthesia, midazolam group applied midazolam assisted anesthesia. compared analysis applied on drugs before and after the hemodynamics changes of two groups, P<0.05, had difference statistically significance. Results Etomidate group drugs before and after the application of mean arterial pressure, heart rate, oxygen saturation, P>0.05,had no difference statistically significance, midazolam group drug before and after application of mean arterial pressure, heart rate, oxygen saturation, P<0.05, had difference statistically signiifcance. Conclusion Etomidate assisted anesthesia has higher security. Not lead respiratory and circulatory higher inhibitory. Therefore, patients after surgery can timely recovery, its more higher safety, especially its application in patients with shock, its advantage can highlighted.