CAJ | 학술논문

自噬是广泛存在于真核细胞内，通过溶酶体清除自身受损细胞器和异常蛋白的过程。在神经系统中，从神经退行性疾病到神经创伤，自噬都发挥了重要作用。深入研究神经细胞自噬发生及其分子调控机制，对全面了解自噬在神经系统疾病中的作用有重要意义。
자서시엄범존재우진핵세포내，통과용매체청제자신수손세포기화이상단백적과정。재신경계통중，종신경퇴행성질병도신경창상，자서도발휘료중요작용。심입연구신경세포자서발생급기분자조공궤제，대전면료해자서재신경계통질병중적작용유중요의의。
Autophagy as a degradative process that widely exists in eukaryotic cells can clear intracellular damaged organelles and protein through lysosomes. It was found in recent studies that autophagy play an important role in neurological disease, both neurodegenerative and neurotraumatic diseases. Comprehensive understanding of autophagy effect and molecular mechanism in different types of neurological diseases can provide new strategies for disease prevention and the treatment. This review mainly focused on the inlfuence of autophagy on neurological diseases.