CAJ | 학술논문

肝衰竭进展迅速,病死率高.为改善预后,糖皮质激素在肝衰竭治疗中应用较多,但是并未得到广泛认可.此文结合国内外最新文献,从肝衰竭的发病机制、糖皮质激素的应用时机、治疗效果和不良反应等方面进行综述,以期提高临床医师对糖皮质激素在肝衰竭治疗中的认识,规范糖皮质激素的临床应用.
간쇠갈진전신속,병사솔고.위개선예후,당피질격소재간쇠갈치료중응용교다,단시병미득도엄범인가.차문결합국내외최신문헌,종간쇠갈적발병궤제、당피질격소적응용시궤、치료효과화불량반응등방면진행종술,이기제고림상의사대당피질격소재간쇠갈치료중적인식,규범당피질격소적림상응용.
Liver failure is characterized by rapid progress and extremely high mortality.Glucocorticoids are currently used in the treatment of liver failure to improve the prognosis,but they have not been widely recognized.This paper reviews the advances on pathogenesis of liver failure,the timing,efficacy and adverse effects of glucocorticoids treatment,so as to increase clinician's knowledge of glucocorticoids in treatment of liver failure,in order to increase the awareness and rational administration of glucocorticoids in treatment of liver failure.