中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2015年
17期
1-3
,共3页
微生物%感染%耐药性
微生物%感染%耐藥性
미생물%감염%내약성
Microorganism%Infection%Drug resistance
目的：了解高明从化地区临床常见致病菌的分布，分析相关致病菌的耐药现状，为临床治疗提供依据。方法1270株细菌培养阳性标本的病原菌，按美国临床实验室标准化委员会(NCCLS)标准进行药物敏感试验，根据药敏结果进行耐药情况分析。结果在检出的1270例病原菌中，革兰阳性菌828株，占检出菌株的65.2%，革兰阴性菌442株，占检出菌株的34.8%。革兰阳性菌以凝固酶阴性葡萄球菌为主，其次是金黄色葡萄球菌、粪肠球菌等；革兰阴性菌以大肠埃希菌为主，其次是奇异变形杆菌、肺炎克雷伯菌等；非发酵菌以铜绿假单胞菌为主，其次是洋葱假单胞菌等。所有送检标本中，共检出真菌280株，成为生殖道送检标本中检出的重要病原菌。各种细菌对相应抗生素出现不同程度的耐药情况。结论条件致病菌成为越来越重要的病原菌，真菌感染有增多的趋势；掌握细菌耐药情况，合理规范使用抗生素，是感染治疗成功及延缓细菌出现耐药的关键。
目的：瞭解高明從化地區臨床常見緻病菌的分佈，分析相關緻病菌的耐藥現狀，為臨床治療提供依據。方法1270株細菌培養暘性標本的病原菌，按美國臨床實驗室標準化委員會(NCCLS)標準進行藥物敏感試驗，根據藥敏結果進行耐藥情況分析。結果在檢齣的1270例病原菌中，革蘭暘性菌828株，佔檢齣菌株的65.2%，革蘭陰性菌442株，佔檢齣菌株的34.8%。革蘭暘性菌以凝固酶陰性葡萄毬菌為主，其次是金黃色葡萄毬菌、糞腸毬菌等；革蘭陰性菌以大腸埃希菌為主，其次是奇異變形桿菌、肺炎剋雷伯菌等；非髮酵菌以銅綠假單胞菌為主，其次是洋蔥假單胞菌等。所有送檢標本中，共檢齣真菌280株，成為生殖道送檢標本中檢齣的重要病原菌。各種細菌對相應抗生素齣現不同程度的耐藥情況。結論條件緻病菌成為越來越重要的病原菌，真菌感染有增多的趨勢；掌握細菌耐藥情況，閤理規範使用抗生素，是感染治療成功及延緩細菌齣現耐藥的關鍵。
목적：료해고명종화지구림상상견치병균적분포，분석상관치병균적내약현상，위림상치료제공의거。방법1270주세균배양양성표본적병원균，안미국림상실험실표준화위원회(NCCLS)표준진행약물민감시험，근거약민결과진행내약정황분석。결과재검출적1270례병원균중，혁란양성균828주，점검출균주적65.2%，혁란음성균442주，점검출균주적34.8%。혁란양성균이응고매음성포도구균위주，기차시금황색포도구균、분장구균등；혁란음성균이대장애희균위주，기차시기이변형간균、폐염극뢰백균등；비발효균이동록가단포균위주，기차시양총가단포균등。소유송검표본중，공검출진균280주，성위생식도송검표본중검출적중요병원균。각충세균대상응항생소출현불동정도적내약정황。결론조건치병균성위월래월중요적병원균，진균감염유증다적추세；장악세균내약정황，합리규범사용항생소，시감염치료성공급연완세균출현내약적관건。
Objective To understand distribution of common clinical pathogenic bacteria in Conghua district of Gaoming city, and to analyze its drug resistance, in order to provide reference for clinical treatment. Methods Drug sensitivity test was applied under national committee for clinical laboratory standards (NCCLS) criterion for 1270 strains of pathogenic bacteria as positive samples. Analysis of drug resistance was made according to drug sensitivity test outcomes. Results Among 1270 detected strains of pathogenic bacteria, there were 828 strains of gram-positive bacterium, accounting for 65.2%, and 442 strains of gram-negative bacterium, accounting for 34.8%. Gram-positive bacterium mainly included coagulase negative staphylococcus, followed by staphylococcus aureus and enterococcus faecalis. Gram-negative bacterium mainly included escherichia coli, followed by proteus mirabilis and Klebsiella pneumonia. Non-fermentative bacterial mainly included pseudomonas aeruginosa, followed by pseudomonas cepacia. There were totally 280 strains of fungus among the detection samples, and those funguses were the main pathogenic bacteria. Different bacteria had various drug resistance levels for corresponding antibiotics.Conclusion Conditioned pathogen has become more and more important as pathogenic bacteria, while fungus also has increasing trend. Control of drug resistance and rational antibiotics usage are the keys for successful infection treatment and drug resistance suspension.
