CAJ | 학술논문

目的：探讨采用白芍总苷胶囊联合窄谱中波紫外线照射治疗斑块型银屑病的疗效及预后，完善临床应用。方法选取于我院就诊的76例斑块型银屑病患者，按随机化原则分为观察组25例、对照组A 26例、对照组B 25例。观察组患者采用白芍总苷胶囊联合窄谱中波紫外线照射治疗，对照组A患者采用单纯NB-UVB照射治疗，对照组B患者采用单纯白芍总苷胶囊治疗。对三组患者的治疗效果和预后情况进行对比分析。结果观察组患者治疗后PASI评分低于两对照组，P＜0.01，差异具有统计学意义；观察组治疗后总有效率高于两对照组，P＜0.05，差异具有统计学意义。结论采用白芍总苷胶囊联合窄谱中波紫外线照射治疗斑块型银屑病疗效确切，副反应轻微，治疗上安全、有效，应用价值高。
목적：탐토채용백작총감효낭연합착보중파자외선조사치료반괴형은설병적료효급예후，완선림상응용。방법선취우아원취진적76례반괴형은설병환자，안수궤화원칙분위관찰조25례、대조조A 26례、대조조B 25례。관찰조환자채용백작총감효낭연합착보중파자외선조사치료，대조조A환자채용단순NB-UVB조사치료，대조조B환자채용단순백작총감효낭치료。대삼조환자적치료효과화예후정황진행대비분석。결과관찰조환자치료후PASI평분저우량대조조，P＜0.01，차이구유통계학의의；관찰조치료후총유효솔고우량대조조，P＜0.05，차이구유통계학의의。결론채용백작총감효낭연합착보중파자외선조사치료반괴형은설병료효학절，부반응경미，치료상안전、유효，응용개치고。
Objective The effect and prognosis of narrow-band ultraviolet B (NB-UVB) combine with total glucosides of paeony on plaque psoriasis. Methods Selected 76 cases with plaque psoriasis in our hospital, divided into observation group with 25 cases, control group A with 26 cases and control group B with 25 cases randomly. Obverstation group was treated with total glucosides of paeony combined with radiation of NB-UVB, control group A treated with radiation of NB-UVB only , control group B treated with glucosides of paeony only. Contrast analyzed the clinical efficiency and prognosis with three groups. Results Observation group PASI scores lower than the control groups after treatment, P<0.01, had difference statistical signiifcance. Observation group cure rate was higher than control group A and B, P<0.05, had difference statistical signiifcance. Conclusion NB-UVB combined with total glucosides of paeony is a safe and effective method to treatment with plaque psoriasis, has slingt side reaction and high application value.