CAJ | 학술논문

目的：探讨新疆地区上尿路结石患儿结石成分分布的民族、性别及年龄差异，为制定治疗方案提供依据。方法采用结石红外光谱自动分析仪对2009年12月至2013年3月入院治疗的762例患儿的上尿路结石标本进行结石成分分析，并结合临床资料进行比较。结果①762例患儿尿路结石的主要类型为含钙结石，占79．0％，男女差异无统计学意义（ P＞0．05）。②患儿年龄以0～5岁为主，占48．7％。不同年龄组患儿的性别分布差异显著，11～15岁患儿中女性占比显著高于男性患儿，其他年龄组男性占比高于女性（ P＜0．05）。③含钙结石和尿酸结石分布存在显著的民族差异（ P＜0．05）。维吾尔族患儿中含钙结石和尿酸结石的比重显著高于汉族和哈萨克族，分别为82．5％、62．1％、65．8％和51．1％、28．8％、30．4％。不同民族之间感染性结石的分布差异无统计学意义（P＞0．05）。④不同年龄组尿酸结石分布差异有统计学意义（P＜0．05），其中11～15岁患儿尿酸结石的比重显著小于其他年龄段患儿；但含钙结石和感染性结石的分布差异无统计学意义（P＞0．05）。结论新疆地区上尿路结石患儿结石成分以含钙结石为主，其次为尿酸结石，维吾尔族男性占比最高。此类患儿的治疗应以外科干预和药物溶石并重。
목적：탐토신강지구상뇨로결석환인결석성분분포적민족、성별급년령차이，위제정치료방안제공의거。방법채용결석홍외광보자동분석의대2009년12월지2013년3월입원치료적762례환인적상뇨로결석표본진행결석성분분석，병결합림상자료진행비교。결과①762례환인뇨로결석적주요류형위함개결석，점79．0％，남녀차이무통계학의의（ P＞0．05）。②환인년령이0～5세위주，점48．7％。불동년령조환인적성별분포차이현저，11～15세환인중녀성점비현저고우남성환인，기타년령조남성점비고우녀성（ P＜0．05）。③함개결석화뇨산결석분포존재현저적민족차이（ P＜0．05）。유오이족환인중함개결석화뇨산결석적비중현저고우한족화합살극족，분별위82．5％、62．1％、65．8％화51．1％、28．8％、30．4％。불동민족지간감염성결석적분포차이무통계학의의（P＞0．05）。④불동년령조뇨산결석분포차이유통계학의의（P＜0．05），기중11～15세환인뇨산결석적비중현저소우기타년령단환인；단함개결석화감염성결석적분포차이무통계학의의（P＞0．05）。결론신강지구상뇨로결석환인결석성분이함개결석위주，기차위뇨산결석，유오이족남성점비최고。차류환인적치료응이외과간예화약물용석병중。
Objective To find the differences of urinary stone composition of children in Xinjiang among different ethnics, genders and age groups and provide evidence for the treatment of those suffered children.Methods Stone IR automatic analyzer was used to analyze stone composition of upper urinary tract calculi specimens from 762 children who were hospitalized between January 2009 and March 2013, and clinical data were compared.Results The analysis of stone composition of 762 children with urinary calculi showed that: ( 1 ) Calcium stones accounted for 79.0%, far more than other types and no significant difference between genders ( P>0.05 ) .( 2 ) Children aged 0 to 5 years accounted for 48.7%.Gender distribution of age groups were significantly different, with female children in 11 to 15 years group accounting for 31.8%, far more than males, and males accounting for more in the other age groups (P<0.05).(3) There were significant ethnic differences in distribution of calcium stones and uric acid stones. The proportion of Uygur children with calcium stones and uric acid stones was significantly greater than Han and Kazak, respectively, with 82.5% versus 62.1%, 65.8% and 51.1% versus 28.8%, 30.4%. No significant difference of infection stones among ethnic groups (P>0.05).(4) Distribution of children with uric acid stones was significantly different (P<0.05) among age groups, and uric acid stones in 11 to 15 age group was significantly less than that in other age groups ( 36.9% versus 50.4% and 49.3%) .The distribution of calcium stones and urinary infection was not significantly different (P>0.05).Conclusions Calcium stones account the highest in urinary stones in children in Xinjiang, followed by uric acid stones, and urinary calculi is more common in Uygur male children than female children.Surgical intervention and drug dissolving should be balanced for the treatment.