CAJ | 학술논문

目的观察氟比洛芬、芬太尼复合咪达唑仑与丙泊酚联合用于人工流产术的临床效果及不良反应。方法ASA分级玉级门诊患者90例随机分为观察组A组(氟比洛芬组)、B组(芬太尼组)和对照组C组(丙泊酚组)各30例。监测患者麻醉前2分钟(T0)、睫毛反射消失后(T1)、宫腔吸引(T2)、手术结束(T3)、患者苏醒时(T4)的平均动脉压、心率、氧饱和度(pulse oxygen saturation,SpO2)情况；记录三组患者注射丙泊酚的疼痛反应,记录麻醉效果、丙泊酚总用药量、术后苏醒时间、不良反应发生率以及患者苏醒时(T5),术后10分钟(T6)、术后20分钟(T7)的视觉模拟(visual analog scale,VAS)评分法。结果A、B两组血液动力学平稳(P<0.01)、丙泊酚用量较少(P<0.01)、苏醒时间快(P<0.01)、不良事件率低(P<0.01)。结论氟比洛芬或芬太尼复合咪达唑仑配伍丙泊酚用于无痛人工流产较单纯应用丙泊酚能明显减少丙泊酚的用量,血液动力学更加平稳,苏醒时间更短,而且在患者的舒适性上氟比洛芬要好于芬太尼。
목적관찰불비락분、분태니복합미체서륜여병박분연합용우인공유산술적림상효과급불량반응。방법ASA분급옥급문진환자90례수궤분위관찰조A조(불비락분조)、B조(분태니조)화대조조C조(병박분조)각30례。감측환자마취전2분종(T0)、첩모반사소실후(T1)、궁강흡인(T2)、수술결속(T3)、환자소성시(T4)적평균동맥압、심솔、양포화도(pulse oxygen saturation,SpO2)정황；기록삼조환자주사병박분적동통반응,기록마취효과、병박분총용약량、술후소성시간、불량반응발생솔이급환자소성시(T5),술후10분종(T6)、술후20분종(T7)적시각모의(visual analog scale,VAS)평분법。결과A、B량조혈액동역학평은(P<0.01)、병박분용량교소(P<0.01)、소성시간쾌(P<0.01)、불량사건솔저(P<0.01)。결론불비락분혹분태니복합미체서륜배오병박분용우무통인공유산교단순응용병박분능명현감소병박분적용량,혈액동역학경가평은,소성시간경단,이차재환자적서괄성상불비락분요호우분태니。
Objective To observe the clinical effects and adverse reactions of flurbiprofen or fentanyl combined with midazolam and propofol for painless artificial abortion. Method 90 patients who were ASA I were randomly divided into three groups :group A ( flurbiprofen) , group B ( fentanyl) and group C( propofol) ,and there were 30 cases in each group. We monitor the patient's MAP, HR, SpO2 2min before anesthesia (T0), after eyelash reflex disap-peared(T1), intrauterine attract (T2), the end of surgery (T3), awake (T4) respectively; And pain response when injecting propofol, anesthesia effects, the total dosage of propofol, postoperative recovery time, incidence of adverse events and VAS scores when patient awake (T5), 10min (T6) and 20min after surgery (T7). Result There was smoothly hemodynamics (P<0. 01), less dosage of propofol (P<0. 01), less recovery time (P<0. 01), low incidence adverse events (P<0. 01). Conclusion The doseage of propofol was less, hemodynamics were more stable, recovery time was shorter on Flurbiprofen or fentanyl combined with midazolam and propofol group compared with simplely propofol group. And flurbiprofen was better than fentanyl on patient's comfort.