CAJ | 학술논문

目的探讨颌下腺肌上皮癌的诊治方法。方法对1999~2013年收治于中国医学科学院肿瘤医院的5例颌下腺肌上皮癌患者进行回顾性分析。结果5例颌下腺肌上皮癌患者均行手术治疗,其中2例行复发灶扩大切除,部分下颌骨切除,胸大肌瓣修复,3例行局部扩大切除。术后1例死亡,1例失访,3例长期存活。结论根治性手术切除是颌下腺肌上皮癌的主要治疗方式。对于病变广泛或姑息手术的患者,可以考虑辅助放疗,但疗效有待进一步研究证实。
목적탐토합하선기상피암적진치방법。방법대1999~2013년수치우중국의학과학원종류의원적5례합하선기상피암환자진행회고성분석。결과5례합하선기상피암환자균행수술치료,기중2례행복발조확대절제,부분하합골절제,흉대기판수복,3례행국부확대절제。술후1례사망,1례실방,3례장기존활。결론근치성수술절제시합하선기상피암적주요치료방식。대우병변엄범혹고식수술적환자,가이고필보조방료,단료효유대진일보연구증실。
Objective To investigate the diagnosis and treatment options of myoepithelial carcinoma derived from submandibular gland. Method From 1999 to 2013, all five cases of submandibular myoepithelial carcinoma, admit-ted to Chinese Academy of Medical Sciences Cancer Hospital, were retrospectively analyzed. Result All five patients underwent surgical treatment. Two cases underwent extended resections of the recurrent lesions and partial resection of the mandible, with reconstruction by pectoralis major muscle flap. The other three underwent local excision. Dur-ing follow-up, one patient died, one was lost, and the other three had long-term survival. Conclusion Radical sur-gery is the main treatment for submandibular gland myoepithelial carcinoma. For locally advanced lesions or pallia-tive options,adjuvant radiotherapy may be considered,but the effects are yet to be confirmed by further studies.