中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2015年
11期
44-44
,共1页
茵陈五苓散%大柴胡汤%肝内胆汁淤积
茵陳五苓散%大柴鬍湯%肝內膽汁淤積
인진오령산%대시호탕%간내담즙어적
The Yinchen Wuling San%The Da Chaihu decoction%Intrahepatic cholestasis
目的：分析不同经典方剂对肝内胆汁淤积大鼠病理组织学的影响。方法：选取30只行肝内胆汁淤积造模大鼠，将其随机分为对照组（生理盐水）、A组（茵陈五苓散）以及B组（大柴胡汤剂）。结果：A组、B组胆管样上皮细胞明显减少、肝细胞明显增多、胶原纤维增生减少且肝组织纤维化程度较轻，且A组较B组明显。结论：方剂可有效改善BDL所引起的肝外胆汁淤积大鼠模型病理组织学改变，尤以茵陈五苓散效果最佳。
目的：分析不同經典方劑對肝內膽汁淤積大鼠病理組織學的影響。方法：選取30隻行肝內膽汁淤積造模大鼠，將其隨機分為對照組（生理鹽水）、A組（茵陳五苓散）以及B組（大柴鬍湯劑）。結果：A組、B組膽管樣上皮細胞明顯減少、肝細胞明顯增多、膠原纖維增生減少且肝組織纖維化程度較輕，且A組較B組明顯。結論：方劑可有效改善BDL所引起的肝外膽汁淤積大鼠模型病理組織學改變，尤以茵陳五苓散效果最佳。
목적：분석불동경전방제대간내담즙어적대서병리조직학적영향。방법：선취30지행간내담즙어적조모대서，장기수궤분위대조조（생리염수）、A조（인진오령산）이급B조（대시호탕제）。결과：A조、B조담관양상피세포명현감소、간세포명현증다、효원섬유증생감소차간조직섬유화정도교경，차A조교B조명현。결론：방제가유효개선BDL소인기적간외담즙어적대서모형병리조직학개변，우이인진오령산효과최가。
Objective: Analysis of different classic recipe for intrahepatic cholestasis histopathology in rats.Methods:30 intrahepatic cholestasis model rats,Randomly divided into control group (saline), A group (Yinchen Wulingsan) and group B (Dachaihu decoction). Results: A, B group significantly reduced bile duct-like epithelial cells, liver cells increased significantly, reducing the collagen fibers and a lesser degree of liver fibrosis. A group was compared with group B. Conclusion: Prescription improve the liver caused by external bile BDL histological changes in rat model of cholestasis, especially the Yinchen Wuling San best.
