医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2015年
21期
43-43,44
,共2页
帕夫林%强直性脊柱炎%患者%安慰剂%效果
帕伕林%彊直性脊柱炎%患者%安慰劑%效果
파부림%강직성척주염%환자%안위제%효과
Pavlin%Ankylosing spondylitis%Patients%Placebo%Ef ect
目的：分析帕夫林治疗强直性脊柱炎临床疗效。方法将2011年3月~2014年5月我：收治的88例强直性脊柱炎患者采用随机分组方式将其均分为观察组44例以及对照组44例，其中对照组患者给予常规治疗联合安慰剂治疗；观察组患者给予常规治疗联合帕夫林治疗。两组患者在经过不同的治疗方案后，对比分析治疗效果等相关指标。结果在经过治疗后，两组BASFI、指地距离以及外周关节痛等指标有显著差异；同时治疗后发现帕夫林不会对肝肾功能造成严重影响。观察组治疗总有效率为86.4%（38/44）；对照组治疗总有效率为68.2%（30/44），两组间比较差异显著（<0.05）。结论针对于强直性脊柱炎患者而言，采用帕夫林治疗具有镇痛、抗炎以及双向免疫调节等多种功效。同时副作用相对较低，具有较好的耐受性，安全性较高。
目的：分析帕伕林治療彊直性脊柱炎臨床療效。方法將2011年3月~2014年5月我：收治的88例彊直性脊柱炎患者採用隨機分組方式將其均分為觀察組44例以及對照組44例，其中對照組患者給予常規治療聯閤安慰劑治療；觀察組患者給予常規治療聯閤帕伕林治療。兩組患者在經過不同的治療方案後，對比分析治療效果等相關指標。結果在經過治療後，兩組BASFI、指地距離以及外週關節痛等指標有顯著差異；同時治療後髮現帕伕林不會對肝腎功能造成嚴重影響。觀察組治療總有效率為86.4%（38/44）；對照組治療總有效率為68.2%（30/44），兩組間比較差異顯著（<0.05）。結論針對于彊直性脊柱炎患者而言，採用帕伕林治療具有鎮痛、抗炎以及雙嚮免疫調節等多種功效。同時副作用相對較低，具有較好的耐受性，安全性較高。
목적：분석파부림치료강직성척주염림상료효。방법장2011년3월~2014년5월아：수치적88례강직성척주염환자채용수궤분조방식장기균분위관찰조44례이급대조조44례，기중대조조환자급여상규치료연합안위제치료；관찰조환자급여상규치료연합파부림치료。량조환자재경과불동적치료방안후，대비분석치료효과등상관지표。결과재경과치료후，량조BASFI、지지거리이급외주관절통등지표유현저차이；동시치료후발현파부림불회대간신공능조성엄중영향。관찰조치료총유효솔위86.4%（38/44）；대조조치료총유효솔위68.2%（30/44），량조간비교차이현저（<0.05）。결론침대우강직성척주염환자이언，채용파부림치료구유진통、항염이급쌍향면역조절등다충공효。동시부작용상대교저，구유교호적내수성，안전성교고。
Objective To analyse clinical curative ef ect of TGP treatment of ankylosing spondylitis.Methods In March 2011~May 2014,our hospital 88 cases of patients with ankylosing spondylitis by random grouping the 44 cases were divided into observation group and control group in 44 cases,the control of these patients were given conventional treatment with placebo therapy;Given conventional treatment combined TGP treatment group patients.Two groups of patients after dif erent treatments,comparison and analysis treatment ef ect and related indicators. Results After treatment,two groups of BASFI,refers to the distance,and peripheral joint pain and other indicators have significant dif erence;After treatment at the same time found the TGP wil not serious ef ects on the liver and kidney function.Treatment group total ef ective rate was 86.4% (38/44);The control group total ef ective rate was 68.2% (30/44),more significant dif erence between the two groups ( <0.05). Conclusion In patients with ankylosing spondylitis,the TGP treatment has analgesic, anti-inflammatory and two-way immunomodulatory ef ect.Side ef ects are relatively low at the same time,has good tolerance and high security.Especial y for inflammation of the tendon at achment points is bet er than other anti-inflammatory drugs,can be used as an auxiliary treatment for a long time,or other drug treatment in patients with ankylosing spondylitis.
