医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2015年
21期
17-17,18
,共2页
骨髓印片%诊断%慢性淋巴细胞白血病%价值
骨髓印片%診斷%慢性淋巴細胞白血病%價值
골수인편%진단%만성림파세포백혈병%개치
Bone mar ow imprint%Diagnosis%Chronic lymphocytic leukemia%Value
目的:研究骨髓印片在慢性淋巴细胞白血病诊断中的应用价值。方法收集2006年5月~2013年12月同步检查骨髓涂片、印片和切片的105例慢性淋巴细胞白血病,以切片为金标准评估骨髓印片与涂片的有核细胞量、淋巴细胞百分比差异及诊断符合率,并观察印片肿瘤细胞的浸润方式。结果骨髓印片的有核细胞量评估性能优于涂片(<0.05),而与切片相近(﹥0.05);骨髓印片成熟淋巴细胞百分比评估性能也优于涂片(<0.05),而与切片相近(﹥0.05);印片诊断符合率为(98.1%),骨髓涂片符合率为(74.3%)骨髓印片诊断符合率高于骨髓涂片(<0.05)。结论骨髓印片兼有涂片和切片的特征。印片评估有核细胞量及细胞百分比、诊断符合率优于涂片,也可预测切片中肿瘤细胞的浸润的某些方式。印片联合涂片互补性检查,对主要依据形态学进行的诊断具有明显优势。
目的:研究骨髓印片在慢性淋巴細胞白血病診斷中的應用價值。方法收集2006年5月~2013年12月同步檢查骨髓塗片、印片和切片的105例慢性淋巴細胞白血病,以切片為金標準評估骨髓印片與塗片的有覈細胞量、淋巴細胞百分比差異及診斷符閤率,併觀察印片腫瘤細胞的浸潤方式。結果骨髓印片的有覈細胞量評估性能優于塗片(<0.05),而與切片相近(﹥0.05);骨髓印片成熟淋巴細胞百分比評估性能也優于塗片(<0.05),而與切片相近(﹥0.05);印片診斷符閤率為(98.1%),骨髓塗片符閤率為(74.3%)骨髓印片診斷符閤率高于骨髓塗片(<0.05)。結論骨髓印片兼有塗片和切片的特徵。印片評估有覈細胞量及細胞百分比、診斷符閤率優于塗片,也可預測切片中腫瘤細胞的浸潤的某些方式。印片聯閤塗片互補性檢查,對主要依據形態學進行的診斷具有明顯優勢。
목적:연구골수인편재만성림파세포백혈병진단중적응용개치。방법수집2006년5월~2013년12월동보검사골수도편、인편화절편적105례만성림파세포백혈병,이절편위금표준평고골수인편여도편적유핵세포량、림파세포백분비차이급진단부합솔,병관찰인편종류세포적침윤방식。결과골수인편적유핵세포량평고성능우우도편(<0.05),이여절편상근(﹥0.05);골수인편성숙림파세포백분비평고성능야우우도편(<0.05),이여절편상근(﹥0.05);인편진단부합솔위(98.1%),골수도편부합솔위(74.3%)골수인편진단부합솔고우골수도편(<0.05)。결론골수인편겸유도편화절편적특정。인편평고유핵세포량급세포백분비、진단부합솔우우도편,야가예측절편중종류세포적침윤적모사방식。인편연합도편호보성검사,대주요의거형태학진행적진단구유명현우세。
Objective To study the value of BM imprint in diagnosis of chronic lymphocytic leukemia. Methods 105 cases of chronic lymphocytic leukemia simultaneous examined of BM smear, imprint and section were col ected from 2006 May to 2013 December.BM smear and imprint were estimated of diagnosis accuracy, percentage of lymphocytes and BM nucleated cel s,by the gold standard of BM sections ,and BM imprint observed the infiltration of cancer cel s. Results BM imprint of nucleated cel s quantity assessment of performance is bet er than that of smear ( <0.05), and were similar with BM section ( >0.05);BM imprint of mature lymphocytes percentage assessment of performance is bet er than that of smear ( <0.05), and were similar with section ( >0.05);the diagnostic accordance rate of BM imprint was (98.1%), BM smear was (74.3%),the diagnostic accordance rate of BM imprint higher than smear ( <0.05). Conclusion BM imprint contains the characteristics of both smear and section. BM imprint is superior to smear for smear for an evaluation of cel ularity .And it is also bet er than section for an analysis of cytological changes.