国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2015年
6期
448-451
,共4页
放射疗法%肿瘤%免疫疗法%旁观者效应
放射療法%腫瘤%免疫療法%徬觀者效應
방사요법%종류%면역요법%방관자효응
Radiotherapy%Neoplasms%Immunotherapy%Bystander effect
肿瘤放疗能够影响机体免疫,最新研究显示适当的放疗方式能够通过调节肿瘤微环境、激活免疫细胞、释放死亡危险信号而激活免疫,产生旁观者或远位效应。随着放疗与免疫联合治疗临床评价指标研究及临床试验的开展,将有望改变传统的肿瘤治疗模式。
腫瘤放療能夠影響機體免疫,最新研究顯示適噹的放療方式能夠通過調節腫瘤微環境、激活免疫細胞、釋放死亡危險信號而激活免疫,產生徬觀者或遠位效應。隨著放療與免疫聯閤治療臨床評價指標研究及臨床試驗的開展,將有望改變傳統的腫瘤治療模式。
종류방료능구영향궤체면역,최신연구현시괄당적방료방식능구통과조절종류미배경、격활면역세포、석방사망위험신호이격활면역,산생방관자혹원위효응。수착방료여면역연합치료림상평개지표연구급림상시험적개전,장유망개변전통적종류치료모식。
Tumor radiation therapy (RT)can affect the immune system.Latest studies show that appropriate RT can activate the immune system through regulating tumor microenvironment,activating immune cells and releasing danger signals,and can produce bystander or abscopal effect.With the development of clini-cal biomarkers research and clinical trials about RT combined with immunotherapy,it is expected to change the traditional pattern of tumor treatment.