中国小儿急救医学
中國小兒急救醫學
중국소인급구의학
CHINESE PEDIATRIC EMERGENCY MEDICINE
2015年
5期
313-315,319
,共4页
捂热综合征%降钙素原
捂熱綜閤徵%降鈣素原
오열종합정%강개소원
Infant muggy syndrome%Procalcitonin
目的:探讨捂热综合征患儿降钙素原( procalcitonin,PCT)升高的特点和临床意义。方法收集2011年11月至2012年4月在我院PICU 住院的23例捂热综合征患儿的资料,按照危重病例评分,分为高危组(5例)、中危组(12例)、低危组(6例)。按照发病前是否合并感染,分为感染组(8例)和非感染组(15例)。以门诊体检的同年龄段婴儿20例为对照组。观察PC T增高与小儿危重病例评分、原发感染及感染指标的关系,并进行多因素分析,探讨捂热综合征时PCT增高的可能原因。结果捂热综合征患儿 PCT 明显升高,高危组患儿 PCT 值(91.5±90.9) ng/ml;中危组患儿 PCT 值(81.1±74.1) ng/ml;低危组患儿P CT值(112.1±74.9) ng/ml,各组PCT值差异无统计学意义(F=0.371,P=0.732)。与对照组比较,捂热综合征患儿的白细胞计数、中性粒细胞比例、C反应蛋白值均升高,差异均有统计学意义( P均<0.05)。感染组患儿PCT值(72.5±74.4) ng/ml,非感染组患儿PCT值(101.5±76.6) ng/ml,两组比较差异无统计学意义( t=0.873,P=0.392)。 PCT升高与捂热后体温升高度数相关性较高( r=-0.362,P=0.049)。结论捂热综合征患儿的PCT增高与捂热过程有关,高热环境激发应激反应,导致PCT增高。
目的:探討捂熱綜閤徵患兒降鈣素原( procalcitonin,PCT)升高的特點和臨床意義。方法收集2011年11月至2012年4月在我院PICU 住院的23例捂熱綜閤徵患兒的資料,按照危重病例評分,分為高危組(5例)、中危組(12例)、低危組(6例)。按照髮病前是否閤併感染,分為感染組(8例)和非感染組(15例)。以門診體檢的同年齡段嬰兒20例為對照組。觀察PC T增高與小兒危重病例評分、原髮感染及感染指標的關繫,併進行多因素分析,探討捂熱綜閤徵時PCT增高的可能原因。結果捂熱綜閤徵患兒 PCT 明顯升高,高危組患兒 PCT 值(91.5±90.9) ng/ml;中危組患兒 PCT 值(81.1±74.1) ng/ml;低危組患兒P CT值(112.1±74.9) ng/ml,各組PCT值差異無統計學意義(F=0.371,P=0.732)。與對照組比較,捂熱綜閤徵患兒的白細胞計數、中性粒細胞比例、C反應蛋白值均升高,差異均有統計學意義( P均<0.05)。感染組患兒PCT值(72.5±74.4) ng/ml,非感染組患兒PCT值(101.5±76.6) ng/ml,兩組比較差異無統計學意義( t=0.873,P=0.392)。 PCT升高與捂熱後體溫升高度數相關性較高( r=-0.362,P=0.049)。結論捂熱綜閤徵患兒的PCT增高與捂熱過程有關,高熱環境激髮應激反應,導緻PCT增高。
목적:탐토오열종합정환인강개소원( procalcitonin,PCT)승고적특점화림상의의。방법수집2011년11월지2012년4월재아원PICU 주원적23례오열종합정환인적자료,안조위중병례평분,분위고위조(5례)、중위조(12례)、저위조(6례)。안조발병전시부합병감염,분위감염조(8례)화비감염조(15례)。이문진체검적동년령단영인20례위대조조。관찰PC T증고여소인위중병례평분、원발감염급감염지표적관계,병진행다인소분석,탐토오열종합정시PCT증고적가능원인。결과오열종합정환인 PCT 명현승고,고위조환인 PCT 치(91.5±90.9) ng/ml;중위조환인 PCT 치(81.1±74.1) ng/ml;저위조환인P CT치(112.1±74.9) ng/ml,각조PCT치차이무통계학의의(F=0.371,P=0.732)。여대조조비교,오열종합정환인적백세포계수、중성립세포비례、C반응단백치균승고,차이균유통계학의의( P균<0.05)。감염조환인PCT치(72.5±74.4) ng/ml,비감염조환인PCT치(101.5±76.6) ng/ml,량조비교차이무통계학의의( t=0.873,P=0.392)。 PCT승고여오열후체온승고도수상관성교고( r=-0.362,P=0.049)。결론오열종합정환인적PCT증고여오열과정유관,고열배경격발응격반응,도치PCT증고。
Objective To investigate the characteristics and clinical significance of increased procal-citonin( PCT) in infant muggy syndrome( IMS) .Methods A total of 23 IMS cases admitted in PICU from Nov 2011 to Apr 2012 were enrolled.All cases were devided into three groups according to pediatric critical illness score,high risk group(n=5),medium risk group(n=12),and mild risk group(n=6).And 23 cases were also divided into infection group and no infection group according to baseline disease before onset.The relationship of PCT and pediatric critical illness score,primary infectino and infection index weer observed, and the possible causes of icn reased PCT in IMS were explored.Twenty age mathc ed infants reec iving exami-nation in clinic served as control gor up.Re sults PCT inrc eased significantly in IMS cases.The PCT level was(91.5 ±90.9) ngm/l ni high risk group,(81.1 ±74.1) ng/ml in medium risk group,and(112.1 ± 74.9) ng/ml in mild risk group,there were no significant differences among trh ee groups( F=0.371,P =0.732).Other infection index like leukocyte conmt,neutrophil and C reactvi e prto ein in IMSg roup were higher thant hose int he cno trol group,and the results had significant differences( P<0.05,reps ectively) .The PCT level was(72.5 ±74.4) ng/ml in infce toi n group,(101.5 ±76.6) ng/ml in no infection rg oup,and there was on sing ificant difference between two groups(t=0.873,P=0.392).There was no relevance be-tween increase of PCT and the incidence of infection before IMS.But PCT had higher correlation to the body tem-perature after IMS(r=-0.362,P=0.049).Conclusion There is correlation between the increased PCT and fever in IMS,and fever in IMS would lead to inflammation and then resulted in the increase of PCT.