刑事技术
刑事技術
형사기술
FORENSIC SCIENCE AND TECHNOLOGY
2015年
3期
244-245
,共2页
法医遗传学%STR基因座%遗传多态性%石家庄地区%汉族
法醫遺傳學%STR基因座%遺傳多態性%石傢莊地區%漢族
법의유전학%STR기인좌%유전다태성%석가장지구%한족
forensic genetics%STR loci%genetic polymorphism%Shijiazhuang area%Han population
目的：调查石家庄汉族人群18个STR基因座的遗传多态性。方法应用DNA TyperTM 15 Plus荧光标记复合扩增系统检测323名石家庄地区汉族无关个体18个STR基因座多态性，计算群体遗传学参数。结果18个STR基因型分布均符合Hardy-Weinberg平衡（P＞0.05），共检出198个等位基因,695个基因型，12个微变异等位基因。结论18个STR基因座在石家庄汉族人群中有较高的遗传多态性。
目的：調查石傢莊漢族人群18箇STR基因座的遺傳多態性。方法應用DNA TyperTM 15 Plus熒光標記複閤擴增繫統檢測323名石傢莊地區漢族無關箇體18箇STR基因座多態性，計算群體遺傳學參數。結果18箇STR基因型分佈均符閤Hardy-Weinberg平衡（P＞0.05），共檢齣198箇等位基因,695箇基因型，12箇微變異等位基因。結論18箇STR基因座在石傢莊漢族人群中有較高的遺傳多態性。
목적：조사석가장한족인군18개STR기인좌적유전다태성。방법응용DNA TyperTM 15 Plus형광표기복합확증계통검측323명석가장지구한족무관개체18개STR기인좌다태성，계산군체유전학삼수。결과18개STR기인형분포균부합Hardy-Weinberg평형（P＞0.05），공검출198개등위기인,695개기인형，12개미변이등위기인。결론18개STR기인좌재석가장한족인군중유교고적유전다태성。
ObjectiveTo investigate genetic polymorphism of 18 STR loci on human chromosomes of Han population in Shijiazhuang.MethodsAllelic frequencies for 18 STR loci and genetic parameters for forensic purpose were calculated. ResultsNo deviations of allelic frequency from Hardy-Weinberg equilibrium expectations were observed (P>0.05). 198 alleles and 695 genotypes were gained. Allele frequencies varied between 0.002 and 0.545; heterozygosity (H) between 0.624 and 0.932; matching probability (Pm) between 0.016 and 0.189; power of discrimination (DP) between 0.811 and 0.984; polymorphism information content (PIC) between 0.580 and 0.910; power exclusion (PE) between 0.321 and 0.861. 12 off-ladder alleles of 8 STR loci were found.Conclusions18 STR loci of Han population in Shijiazhuang are with relatively high polymorphism, and suitable for forensic individual identiifcation, paternity testing, and relative research.
