医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2015年
20期
340-340
,共1页
何茜%罗建华%范元硕%于瑞萍%董健
何茜%囉建華%範元碩%于瑞萍%董健
하천%라건화%범원석%우서평%동건
抗甲状腺%症状%治疗
抗甲狀腺%癥狀%治療
항갑상선%증상%치료
Anti thyroid%Symptoms%Treatment
抗甲状腺药物(antithyroid drugs,ATD)是治疗Graves甲亢的3种疗法之一,主要有甲巯咪唑(methimazole, MMI)、丙硫氧嘧啶(propylthiouracil,PTU),适用于病情轻、甲状腺轻中度肿大的甲亢患者。中毒性肝病是ATD的副作用之一,其发生率为0.5%~1%,表现为变态反应性肝炎,转氨酶上升,多在用药后3 w发生。本例患者肝功能损害发生极为严重且急骤尚不多见,现将病例报道如下。
抗甲狀腺藥物(antithyroid drugs,ATD)是治療Graves甲亢的3種療法之一,主要有甲巰咪唑(methimazole, MMI)、丙硫氧嘧啶(propylthiouracil,PTU),適用于病情輕、甲狀腺輕中度腫大的甲亢患者。中毒性肝病是ATD的副作用之一,其髮生率為0.5%~1%,錶現為變態反應性肝炎,轉氨酶上升,多在用藥後3 w髮生。本例患者肝功能損害髮生極為嚴重且急驟尚不多見,現將病例報道如下。
항갑상선약물(antithyroid drugs,ATD)시치료Graves갑항적3충요법지일,주요유갑구미서(methimazole, MMI)、병류양밀정(propylthiouracil,PTU),괄용우병정경、갑상선경중도종대적갑항환자。중독성간병시ATD적부작용지일,기발생솔위0.5%~1%,표현위변태반응성간염,전안매상승,다재용약후3 w발생。본례환자간공능손해발생겁위엄중차급취상불다견,현장병례보도여하。
Anti thyroid drugs(ATD)is one of the 3 kinds of therapy in the treatment of Graves'hyperthyroidism,mainly methimazole(MMI),propylthiouracil(PTU),suitable for the condition is light,light to moderate enlargement of the thyroid gland in patients with hyperthyroidism.Poisoning liver disease is one of the side ef ects of ATD,the incidence rate of 0.5%-1%,manifested as al ergic hepatitis, transaminase rise,in 3 weeks after medication occur ed.The patients with liver function damage occurs extremely severe and abrupt stil does not see more,now the case reports are as fol ows.