CAJ | 학술논문

目的：单膝关节置换术后常规使用抗凝药物预防血栓，比较低分子肝素钙与利伐沙班两种抗凝药物，观察二者对于术后失血量的影响。方法回顾性分析2013年7月～2014年1月接受单膝关节置换术的114例患者，其中64例选择利伐沙班进行术后抗凝，50例选择低分子肝素钙进行抗凝，计算术前、术后第一、三、五天的失血量，二者进行统计学分析比较。结果两组失血量进行组间比较，使用独立样本T检验，结果均显示P＞0.05，无显著差异。再将两组的术后第三天较术后第一天增加的失血量进行比较，P＞0.05，无显著差异。将两组的术后第五天较术后第三天增加的失血量进行比较，P＞0.05，也无显著差异。结论单膝置换术后在增加术后失血量方面两种抗凝药无显著差异。
목적：단슬관절치환술후상규사용항응약물예방혈전，비교저분자간소개여리벌사반량충항응약물，관찰이자대우술후실혈량적영향。방법회고성분석2013년7월～2014년1월접수단슬관절치환술적114례환자，기중64례선택리벌사반진행술후항응，50례선택저분자간소개진행항응，계산술전、술후제일、삼、오천적실혈량，이자진행통계학분석비교。결과량조실혈량진행조간비교，사용독립양본T검험，결과균현시P＞0.05，무현저차이。재장량조적술후제삼천교술후제일천증가적실혈량진행비교，P＞0.05，무현저차이。장량조적술후제오천교술후제삼천증가적실혈량진행비교，P＞0.05，야무현저차이。결론단슬치환술후재증가술후실혈량방면량충항응약무현저차이。
OBJECTIVE Anticoagulation is used normally after total knee arthroplasty ( TKA).To compare the effects of lowmolecular weight heparin calcium and rivaroxaban on blood loss after TKA.METHODS A retrospec-tive analysis was made on the clinical data of 114 patients with osteoarthritis ( OA) who underwent TKA between July 2013 and January 2014.The number of rivaroxaban group was 64 ,and LMWH group was 50.The total blood loss was calculated according to the formula at the time of preoperation,the first day,the third day and the fifth day after oper-ation.RESULTS The total blood loss of two groups was compared using independent-sample T test at the time of preoperation,the first day,the third day and the fifth day after operation.All the results were no significant difference ( P>0.05 ).CONCLUSION There is no significant difference in the raise of total blood loss after TKA between the rivaroxaban and LMWH.