CAJ | 학술논문

探讨右美托咪定经鼻腔黏膜给药全麻诱导方式在小儿手术中的应用效果。选择全麻手术患儿120例，据右美托咪定用量，采用随机数字表法分为：4μg／kg、6μg／kg、8μg／kg、10μg／kg组，每组各30例。术前30min将右美托咪定快速注入鼻腔，每侧各半量。采用Berggen、Riker方法评价效果并观察术后有无“迟延模仿”及行为异常发生。结果显示：10μg／kg组镇静效果最好，躁动发生例数、“迟延模仿”与行为异常的发生例数明显少于其他三组（P＜0．05）。右美托咪定经鼻腔黏膜给药的麻醉诱导方式，患儿镇静效果良好，可减少患儿术后躁动及行为异常的发生，益于儿童健康发育。
탐토우미탁미정경비강점막급약전마유도방식재소인수술중적응용효과。선택전마수술환인120례，거우미탁미정용량，채용수궤수자표법분위：4μg／kg、6μg／kg、8μg／kg、10μg／kg조，매조각30례。술전30min장우미탁미정쾌속주입비강，매측각반량。채용Berggen、Riker방법평개효과병관찰술후유무“지연모방”급행위이상발생。결과현시：10μg／kg조진정효과최호，조동발생례수、“지연모방”여행위이상적발생례수명현소우기타삼조（P＜0．05）。우미탁미정경비강점막급약적마취유도방식，환인진정효과량호，가감소환인술후조동급행위이상적발생，익우인동건강발육。
This article is to investigate the effects of general anesthesia induction mode by dexmedetomidine delivered through nasal cavity .120 children undergoing general anesthesia ,scheduled for 4 groups (n= 30):4mg/kg ,6mg/kg , 8mg/kg and 10mg/kg .The dexmedetomidine was delivered quickly into nasal cavity with the same dose each side ,30 min before operation .Berggen and Riker methods were used to value the effects .The time of each group children from the medicine used to sleeping and sedation were recorded .To investigate the "lated imitation" phenomenon and abnormal behavior occurred or no after operation .The results indicated that the sedative effect of 10mg/kg group was the best ;"deferred imitation"and"abnormal behavior"occurred were less than that in the rest (P<0 .05) .The general anesthesia induction mode of dexmedetomidine delivered through nasal cavity had well sedation ,decrease the occurrence of "abnormal behavior"were decreased ,and benefited children's health .